Results 111 to 120 of about 4,279,285 (309)

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Resolution 54.52.09R: Supporting Immigrant Rights

open access: yes, 2009
In this Resolution, the City of Albany Common Council calls on all state, federal, and local political leaders and agencies to refrain from all unnecessary measures to jail, detain, or deport migrants and their families living in the City of Albany.
City of Albany Common Council [NY]
core  

Case count metric for comparative analysis of entity resolution results

open access: yesFrontiers in Big Data
IntroductionEntity resolution (ER) systems often produce different clustering outcomes when applied to the same dataset, especially when parameters, algorithms, or system configurations change.
John R. Talburt   +6 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Appropriate dispute resolution deskbook

open access: yes, 1997
Title from PDF title page (viewed on February 15, 2019).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Handbook for public policy decision-making and conflict resolution

open access: yes, 2006
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF title page (viewed on Nov.

core  

Resolution: Virginia House of Delegates Joint Resolution No. 5, January 11, 1956

open access: yes, 1956
Resolution: 1 pg., photocopy 9.4" X 6.7" (24cm x 17cm)Virginia House of Delegates Joint Resolution No. 5, establishing a Northern Virginia branch of the University of Virginia.

core   +1 more source

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