Results 131 to 140 of about 3,605,424 (316)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Resolution 36-13 (CM): Comprehensive Immigration Reform
, 2013 In this Resolution, the City Council of the City of Watsonville urges the United States 113th Congress to enact comprehensive immigration reform that addresses full legalization with a path to citizenship and future immigration of families and ...
City Council of the City of Watsonville [CA]
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Resolution 59877: Establishing a New Legalization Program
, 2002 In this Resolution, ID No. 32296, the Common Council of the City of Madison urges the United States Congress to establish a new legalization program to allow noncitizens to obtain legal residency in the United ...
Common Council of the City of Madison [WI]
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Resolution 277.08: Reaffirming the Safe Space Policy
, 2008 In this Resolution, the Corporate Authorities of the Town authorize the Town President to reaffirm the Town of Cicero's Safe Space ...
Town of Cicero's President (the "President") and the Board of Trustees of the Town (the "Town Board" and with the President, the "Corporate Authorities") [IL]
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Resolution: Concern with the “USA Patriot Act”
, 2005 In this Resolution, the Haines Borough Assembly states concern that the “USA Patriot Act” threatens civil rights guaranteed under the United States Constitution and opposes any portion of the “USA Patriot Act” that would violate State or federal ...
Haines Borough Assembly [AK]
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NP animacy identification for anaphora resolution
, 2007 In anaphora resolution for English, animacy identification can play an integral role in the application of agreement restrictions between pronouns and candidates, and as a result, can improve the accuracy of anaphora resolution systems.
Evans, Richard, Orasan, Constantin
core +1 more source