Results 121 to 130 of about 4,279,285 (309)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Resolution 170: Secure Communities Program
In this Resolution, the City Council of the City of Providence requests that the Commissioner of Public Safety, and the Chief of the Providence Police Department, review the Secure Communities initiative.
City Council of the City of Providence [RI]
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Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Resolution 2011-504: Civil Immigration Detainer Requests
In this Resolution, the Board of Supervisors of the County of Santa Clara amend the Supervisors' policy manual to add Section 3.54 about civil immigration detainer ...
Board of Supervisors of the County of Santa Clara [CA]
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Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Resolution of the City of Chelsea
In this Resolution, the Chelsea City Council resolves that the City of Chelsea go on record as a Sanctuary ...
Chelsea City Council [MA]
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‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Resolution CR-78-2003: Preserving the Constitutional Rights of Residents
In this Resolution, the County Council of Prince George's County affirms its commitment to democracy, human rights, and civil liberties for all and to the avoidance of discrimination in every function of County government.
County Council of Prince George's County [MD]
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Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source

