Results 41 to 50 of about 3,407,911 (288)

Simulation of Particle Structure Rearrangement and Reaction in Wall-Flow Filters at High Flow Velocities with Lattice Boltzmann Methods

Fluids
Wall-flow filters are used in exhaust gas after treatment systems to reduce particulate matter emissions from internal combustion engines. The particles accumulate on the filter surface during operation, forming a layer that progressively increases the ...
Christoph Gaul, Ole Desens, Pascal Ernst, Andreas Nettekoven, Achim Dittler, Mathias J. Krause   +5 more
doaj   +1 more source

Numerical simulation and optimization of dry bead mill based on DEM [PDF]

AIP Advances
To decouple the effects of geometric and operational parameters on dry grinding performance, we resolved the single-phase particle field of a dry bead mill employing discrete element method simulations.
Chiwei Huang, Jianxuan Chen
doaj   +1 more source

Efficient and scalable hybrid fluid-particle simulations with geometrically resolved particles on heterogeneous CPU-GPU architectures

, 2023
This dataset contains performance results (*.out), corresponding job scripts (*.sh), an evaluation script (evaluate.py), a snapshot of the waLBerla framework (walberla.zip), and build information (build.sh, build.out) for the following paper: "Efficient ...
Köstler, Harald, Kemmler, Samuel, Rettinger, Christoph   +2 more
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Simulation of particle formation and number concentration over the Eastern United States with the WRF-Chem + APM model [PDF]

Atmospheric Chemistry and Physics, 2011
Aerosol nucleation events, widely observed at various locations around the globe, are a significant source of cloud condensation nuclei (CCN) which determines aerosol indirect radiative forcing.
G. Luo, F. Yu
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Enhancing Potential of Trimethylamine Oxide on Atmospheric Particle Formation

Atmosphere, 2019
The role of an oxidation product of trimethylamine, trimethylamine oxide, in atmospheric particle formation is studied using quantum chemical methods and cluster formation simulations.
Nanna Myllys, Tuomo Ponkkonen, Sabrina Chee, James Smith   +3 more
doaj   +1 more source

The Role of Secondary Particle Information in Microstructure-Resolved Simulations [PDF]

ECS Meeting Abstracts, 2021
Wiedemann, Johannes, Danner, Timo, Hein, Simon, Latz, Arnulf   +3 more
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source