Results 61 to 70 of about 3,407,911 (288)

Coupling remote sensing and particle tracking to estimate trajectories in large water bodies

International Journal of Applied Earth Observations and Geoinformation, 2022
Propelled by the rapid development of equipment, technology and computational power, the monitoring and simulation of the hydrodynamics in lakes have steadily advanced.
Chaojie Li, Daniel Odermatt, Damien Bouffard, Alfred Wüest, Tamar Kohn   +4 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

A Full-Field Crystal Plasticity Study on the Bauschinger Effect Caused by Non-Shearable Particles and Voids in Aluminium Single Crystals

Metals
In the present work, the goal is to use two-scale simulations to be incorporated into the full-field open software DAMASK version 2.0.3 crystal plasticity framework, in relation to the Bauschinger effect caused by the composite effect of the presence of ...
Arash Imani Aria, Bjørn Holmedal, Tomas Mánik, Knut Marthinsen   +3 more
doaj   +1 more source

TChem-atm (v2.0.0): scalable performance-portable multiphase atmospheric chemistry [PDF]

Geoscientific Model Development
We present TChem-atm, a performance-portable approach that enables efficient simulation of chemically detailed and multiphase atmospheric chemistry on modern heterogeneous computing architectures.
O. H. Díaz-Ibarra, S. G. Frederick, J. H. Curtis, Z. D'Aquino, P. A. Bosler, L. Patel, C. Safta, M. West, N. Riemer   +8 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Particle-resolved simulations of settling particles: a methodology for long time-integration intervals

Acta Mechanica
Abstract We present a methodology for simulating dilute suspensions of particles settling under gravity, with the main purpose of overcoming limitations of triply periodic configurations, mainly the strong vertical correlation that hinders the study of cluster dynamics.
Moriche, M., García-Villalba, M., Uhlmann, M.   +2 more
openaire   +2 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Evaluation of particle size effect on two-phase flow distribution in a hydrotreatment reactor guard bed using particle-resolved CFD simulations

Chimica Techno Acta
Trickle bed reactors with solid catalyst pellets are important and widely used large-scale apparatuses in the chemical and oil refining industries. In order to reduce the effects of poisons on the catalyst bed and to extend the catalyst loading service ...
Ivan A. Mik, Oleg P. Klenov, Ivan S. Golubev, Pavel P. Dik, Sergey I. Reshetnikov, Alexandr S. Noskov   +5 more
doaj   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

New developments in point-particle simulation: insights from particle-resolved simulations and theory

, 2019
The Eulerian-Lagrangian point-particle method has become a leading paradigm in the study of dispersed particle-laden flows. This strategy simultaneously represents the non-continuum physics of the dispersed phase coupled to the continuum physics of the ...
Horwitz, Jeremy
core   +1 more source