Results 61 to 70 of about 3,274,048 (287)

Wall effects in particle-laden flows [PDF]

, 2011
The aim of this study is to investigate about the complex phenomenology associated with the interaction of a particle-laden turbulent flow with the slag-covered wall of an entrained-flow gasifier.
Ambrosino, Fiorenzo
core   +1 more source

The impact of aerosol mixing state on immersion freezing: insights from classical nucleation theory and particle-resolved simulations [PDF]

Atmospheric Chemistry and Physics
Immersion freezing, initiated by ice-nucleating particles (INPs) in supercooled aqueous droplets, plays an important role in the formation of ice crystals within clouds.
W. Tang, S. Arabas, J. H. Curtis, D. A. Knopf, M. West, N. Riemer   +5 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

A high-efficiency pseudo-homogeneous model for coupled heat and moisture transfer during ventilation drying of maize grain piles

Case Studies in Thermal Engineering
To accurately predict heat and moisture transfer during ventilation drying in maize storage facilities, a computationally efficient pseudo-homogeneous model (PHM) was developed. By incorporating porosity distributions from particle-resolved computational
Wenlei Liu, Rufang Guo, Xulong Zhang, Panqi Wang, Ranran Wang   +4 more
doaj   +1 more source

Measurements and Prediction of Ash Deposition in a Cyclone-Fired Boiler Operating under Variable Load Conditions

Fluids, 2023
Measurements of ash deposition rates were made between the secondary superheater and reheater sections of a 450 MW cyclone-fired lignite boiler as the operational load varied from 33 to 100%.
Gautham Krishnamoorthy, Evan Bloom, Krishnamoorthy Viswanathan, Shuchita Sanjay Patwardhan, David John Stadem, Steve Benson   +5 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

A Full-Field Crystal Plasticity Study on the Bauschinger Effect Caused by Non-Shearable Particles and Voids in Aluminium Single Crystals

Metals
In the present work, the goal is to use two-scale simulations to be incorporated into the full-field open software DAMASK version 2.0.3 crystal plasticity framework, in relation to the Bauschinger effect caused by the composite effect of the presence of ...
Arash Imani Aria, Bjørn Holmedal, Tomas Mánik, Knut Marthinsen   +3 more
doaj   +1 more source

TChem-atm (v2.0.0): scalable performance-portable multiphase atmospheric chemistry [PDF]

Geoscientific Model Development
We present TChem-atm, a performance-portable approach that enables efficient simulation of chemically detailed and multiphase atmospheric chemistry on modern heterogeneous computing architectures.
O. H. Díaz-Ibarra, S. G. Frederick, J. H. Curtis, Z. D'Aquino, P. A. Bosler, L. Patel, C. Safta, M. West, N. Riemer   +8 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Continuity waves in resolved-particle simulations of fluidized beds

Physical Review Fluids, 2017
The results of a fully resolved simulation of up to 2000 spheres suspended in a vertical liquid stream are analyzed by a method based on a truncated Fourier series expansion. It is shown that, in this way, it is possible to identify continuity (or kinematic) waves and to determine their velocity, which is found to closely agree with the theory of one ...
Willen, Daniel P., Sierakowski, Adam J., Zhou, Gedi, Prosperetti, Andrea   +3 more
openaire   +2 more sources