Results 91 to 100 of about 6,962 (307)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
New Perturbed Proximal Point Algorithms for Set-valued Quasi Variational Inclusions
, 2004 In this paper, by using some new and innovative techniques, some perturbed iterative algorithms for solving generalized set-valued variational inclusions are suggested and analyzed.
Li, Rong, Shi, Chaofeng
core
The resolvent average for positive semidefinite matrices
, 2009 We define a new average – termed the resolvent average – for positive semidefinite matrices. For positive definite matrices, the resolvent average enjoys self-duality and it interpolates between the harmonic and the arithmetic averages, which it ...
Heinz H. Bauschke +5 more
core +1 more source
Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Modelûvannâ, 2017 В работе исследуется свойство гьольдеровой непрерывности обратного отображения, определяющего матрицу коэффициентов диффузии A(x) в главной части квази-линейного эллиптического уравнения с анизотропным p-лапласианом как функцию оператора резольвенты ...
P. I. Kogut, O. P. Kupenko
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Identification of External Force Dynamics in The Modeling of Vibration
Известия Иркутского государственного университета: Серия "Математика", 2017 The linear homogeneous wave equations with initial and boundary conditions are considered. It is assumed that the non-uniform terms describing an external force, are expanded into Fourier series, and the objective is to determine its N time depending ...
A.I. Dreglea, N.A. Sidorov
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Approximation processes for resolvent operators
, 2008 We introduce some general sequences of linear operators obtained from classical approximation processes which turn to be useful in the approximation of the resolvent operators of the generator of suitable C_0-semigroups.
TACELLI, CRISTIAN, CAMPITI, Michele
core +1 more source
SPAСETIME ANALYSIS OF AN ELECTROMAGNETIC AIRY PULSE AFTER ITS INTERACTION WITH A PLANAR BOUNDARY IN UNIFORMLY ACCELERATED RELATIVISTIC MOTION [PDF]
Radio Physics and Radio AstronomySubject and Purpose. The transformation peculiarities that the electromagnetic pulses get when heading towards a boundary that performs uniformly accelerated relativistic motion are the present paper concern.
O. V. Zhyla, N. P. Stognii
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source