Results 111 to 120 of about 9,486 (287)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Browder S-resolvent equation in quaternionic setting [PDF]
This paper is devoted to the study of the S-eigenvalue of finite type of a bounded right quaternionic linear operator acting in a right quaternionic Hilbert space. The study is based on the different properties of the Riesz projection associated with the
Baloudi, H., Zmouli, H., Jeribi, A.
core
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
The resolvent average for positive semidefinite matrices [PDF]
We define a new average – termed the resolvent average – for positive semidefinite matrices. For positive definite matrices, the resolvent average enjoys self-duality and it interpolates between the harmonic and the arithmetic averages, which it ...
Heinz H. Bauschke +5 more
core +1 more source
Powersum formula for polynomials whose distinct roots are differentially independent over constants
We prove that the author's powersum formula yields a nonzero expression for a particular linear ordinary differential equation, called a resolvent, associated with a univariate polynomial whose coefficients lie in a differential field of characteristic ...
John Michael Nahay
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Resolvent estimates for 2-dimensional perturbations of plane Couette flow
We present results concerning resolvent estimates for the linear operator associated with the system of differential equations governing 2 dimensional perturbations of plane Couette flow.
Pablo Braz e Silva
doaj
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Differential resolvents of minimal order and weight
We will determine the number of powers of α that appear with nonzero coefficient in an α-power linear differential resolvent of smallest possible order of a univariate polynomial P(t) whose coefficients lie in an ordinary differential field and whose ...
John Michael Nahay
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source

