Results 111 to 120 of about 9,486 (287)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Browder S-resolvent equation in quaternionic setting [PDF]

open access: yes, 2023
This paper is devoted to the study of the S-eigenvalue of finite type of a bounded right quaternionic linear operator acting in a right quaternionic Hilbert space. The study is based on the different properties of the Riesz projection associated with the
Baloudi, H., Zmouli, H., Jeribi, A.
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The resolvent average for positive semidefinite matrices [PDF]

open access: yes, 2009
We define a new average – termed the resolvent average – for positive semidefinite matrices. For positive definite matrices, the resolvent average enjoys self-duality and it interpolates between the harmonic and the arithmetic averages, which it ...
Heinz H. Bauschke   +5 more
core   +1 more source

Powersum formula for polynomials whose distinct roots are differentially independent over constants

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2002
We prove that the author's powersum formula yields a nonzero expression for a particular linear ordinary differential equation, called a resolvent, associated with a univariate polynomial whose coefficients lie in a differential field of characteristic ...
John Michael Nahay
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Resolvent estimates for 2-dimensional perturbations of plane Couette flow

open access: yesElectronic Journal of Differential Equations, 2002
We present results concerning resolvent estimates for the linear operator associated with the system of differential equations governing 2 dimensional perturbations of plane Couette flow.
Pablo Braz e Silva
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Differential resolvents of minimal order and weight

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2004
We will determine the number of powers of α that appear with nonzero coefficient in an α-power linear differential resolvent of smallest possible order of a univariate polynomial P(t) whose coefficients lie in an ordinary differential field and whose ...
John Michael Nahay
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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