Results 121 to 130 of about 11,871 (292)
Variational-Like Inclusions and Resolvent Equations Involving Infinite Family of Set-Valued Mappings
We study variational-like inclusions involving infinite family of set-valued mappings and their equivalence with resolvent equations. It is established that variational-like inclusions in real Banach spaces are equivalent to fixed point problems.
Ahmad Rais, Dilshad Mohd
doaj
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Resolving thromboinflammation [PDF]
Stephen P. McAdoo, Neeraj Dhaun
openaire +2 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Quaternionic resolvent equation and series expansion of the $\mathcal{S}$-resolvent operator
In the present paper, we prove a resolvent equation for the $\mathcal{S}$-resolvent operator in the quaternionic framework. Exploiting this resolvent equation, we find a series expansion for the $\mathcal{S}$-resolvent operator in an open neighborhood of
Ghiloni, Riccardo, Recupero, Vincenzo
core
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
ON THE RESOLVENT OF SOME CLASS OF GENERALIZED DIFFERENTIAL OPERATOR
In the article is given representation of the resolvent for generalized differential operator with generating function in the space of holomorphic functions.
A.V. BRATISHCHEV, A.V. MORZHAKOV
doaj

