Results 121 to 130 of about 6,962 (307)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
IMPROVED RESOLVENT BOUNDS FOR RADIAL POTENTIALS. II
, 2022 International audienceWe prove semiclassical resolvent estimates for the Schrödinger operator in R d , d ≥ 3, with real-valued radial potentials V ∈ L ∞ (R d).
Vodev, Georgi
core +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Norm-resolvent convergence in perforated domains
, 2018 For several different boundary conditions (Dirichlet, Neumann, Robin), we prove norm-resolvent convergence for the operator −Δ in the perforated domain Ω∖⋃i∈2εZdBaε(i), aε≪ε, to the limit operator −Δ+μι on L2(Ω), where μι∈Cis a constant depending on the ...
Rösler, Frank +2 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Some resolvent methods for general variational inclusions
, 2011 In this paper, we consider and analyze some classes of resolvent-splitting methods for solving the general variational inclusions using the technique of updating the solution.
Al-Said, Eisa +5 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Resolvent bounds for jump generators
, 2018 Kondratiev Y, Molchanov S, Piatnitski A, Zhizhina E. Resolvent bounds for jump generators. APPLICABLE ANALYSIS. 2018;97(3):323-336.The paper deals with jump generators with a convolution kernel.
Molchanov, Stanislav +3 more
core +1 more source
A local directional growth estimate of the resolvent norm
, 2018 We study the resolvent norm of a certain class of closed linear operators on a Hilbert space, including unbounded operators with compact resolvent. It is shown that for any point in the resolvent set there exist directions in which the norm grows at ...
Cornean, Decebal Horia; id_orcid +3 more
core +1 more source