Results 131 to 140 of about 11,871 (292)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Resolvent-Generated Generalized Spectral Operators for Nonlinear Dynamical Systems via Koopman Semigroups

open access: yesMathematics
Spectral methods form a cornerstone of linear dynamics, where evolution is resolved into harmonic modes governed by eigenvalues and spectral measures of normal operators.
Rui A. P. Perdigão
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Transfer functions and resolvent norm approximation of large matrices

open access: yes, 1998
. A unifying framework for methods employed in the approximation of the resolvent norm of nonnormal matrices is presented. This formulation uses specific transfer functions, and it provides new information about the approximation properties of these ...
V. Simoncini, E. Gallopoulos
core  

The resolvent average for positive semidefinite matrices

open access: yes, 2009
We define a new average – termed the resolvent average – for positive semidefinite matrices. For positive definite matrices, the resolvent average enjoys self-duality and it interpolates between the harmonic and the arithmetic averages, which it ...
Heinz H. Bauschke   +2 more
core   +1 more source

Resolvents for Convex Functions on Geodesic Spaces and Their Nonspreadingness

open access: yesAxioms
The convex optimization problems have been considered by many researchers on geodesic spaces. In these problems, the resolvent operators play an important role.
Takuto Kajimura   +2 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Iterated resolvent estimates for power bounded matrices [PDF]

open access: yes, 2010
We discuss analogs of the Kreiss resolvent condition for power bounded matrices.
Zarouf, Rachid
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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