Results 71 to 80 of about 1,287,488 (289)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Resolving the singularities of differential equations
Sheaf theoretic methods are used to convert an implicit analytic differential equation into an explicit one. Applications to the study of singular solutions and to Morse theory are given.
openaire +3 more sources
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
On the Resolvent of the Laplace-Beltrami Operator in Hyperbolic Space
In this paper, a detailed description of the resolvent of the Laplace-Beltrami operator in n-dimensional hyperbolic space is given. The resolvent is an integral operator with the kernel (Green's function) being a solution of a hypergeometric differential
Guseinov, Gusein Sh.
core +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Hill's equation for a homogeneous tree
The analysis of Hill's operator $-D^2 + q(x)$ for $q$ even and periodic is extended from the real line to homogeneous trees ${cal T}$. Generalizing the classical problem, a detailed analysis of Hill's equation and its related operator theory on $L^2({cal
Robert Carlson
doaj
Resolvent Estimates Related with a Class of Dispersive Equations [PDF]
We present a simple proof of the resolvent estimates of elliptic Fourier multipliers on the Euclidean space, and apply them to the analysis of time-global and spatially-local smoothing estimates of a class of dispersive equations. For this purpose we study in detail the properties of the restriction of Fourier transform on the unit cotangent sphere ...
openaire +2 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
This article studies the structure and properties of real-ordered Hilbert spaces, highlighting the roles of the XOR and XNOR logical operators in conjunction with the Yosida and Cayley approximation operators.
Arifuzzaman +2 more
doaj +1 more source

