Results 101 to 110 of about 519,621 (251)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

On negative eigenvalues of 1D Schrödinger operators with δ′-like potentials

Frontiers in Applied Mathematics and Statistics
In this paper, we investigate negative eigenvalues of exactly solvable quantum models, particularly one-dimensional Hamiltonians with δ′-like potentials used to represent localized dipoles.
Yuriy Golovaty, Rostyslav Hryniv, Rostyslav Hryniv   +2 more
doaj   +1 more source

A Proximal Point Method Involving Two Resolvent Operators

Abstract and Applied Analysis, 2012
We construct a sequence of proximal iterates that converges strongly (under minimal assumptions) to a common zero of two maximal monotone operators in a Hilbert space. The algorithm introduced in this paper puts together several proximal point algorithms
Oganeditse A. Boikanyo
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Spectral Distribution of Transport Operator Arising in Growing Cell Populations

Journal of Function Spaces, 2014
Transport equation with partly smooth boundary conditions arising in growing cell populations is studied in Lp ...
Hongxing Wu, Shenghua Wang, Dengbin Yuan
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Iterative Algorithms for New General Systems of Set-Valued Variational Inclusions Involving (A,η)-Maximal Relaxed Monotone Operators

Journal of Applied Mathematics, 2014
We introduce and study a class of new general systems of set-valued variational inclusions involving (A,η)-maximal relaxed monotone operators in Hilbert spaces.
Ting-jian Xiong, Heng-you Lan
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Weighted resolvent estimates for Volterra operators on unbounded intervals

, 1990
Rejto, Peter; Taboada, Mario. (1990). Weighted resolvent estimates for Volterra operators on unbounded intervals.
Taboada, Mario, Rejto, Peter
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