Results 111 to 120 of about 519,621 (251)
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Pseudo-differential operators, heat calculus and index theory of groupoids satisfying the Lauter-Nistor condition [PDF]
In this thesis, we study singular pseudo-differential operators defined by groupoids satisfying the Lauter-Nistor condition, by a method parallel to that of manifolds with boundary and edge differential operators.
So, Bing Kwan
core
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Journal of Applied Mathematics, 2011 The existence of the solution for a new system of generalized nonlinear mixed quasi variational inclusions with H-monotone operators is proved by using implicit resolvent technique, and the sensitivity analysis of solution in Hilbert spaces is given ...
Han-Wen Cao
doaj +1 more source
Generalized resolvents of operators generated by integral equations
Issues of Analysis, 2018 Summary: We define a minimal operator \(L_0\) generated by an integral equation with an operator measure and give a description of the adjoint operator \(L^*_0\). We prove that every generalized resolvent of \(L_0\) is an integral operator and give a description of boundary value problems associated to generalized resolvents.
openaire +2 more sources
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
A Gauss Laguerre approach for the resolvent of fractional powers
, 2022 This paper introduces a very fast method for the computation of the resolvent of fractional powers of operators. The analysis is kept in the continuous setting of (potentially unbounded) self adjoint positive operators in Hilbert spaces.
Denich, Eleonora +2 more
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Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
On the convergence of resolvents of operators [PDF]
Pacific Journal of Mathematics, 1967 openaire +3 more sources