Results 111 to 120 of about 4,831,190 (292)

Overlarge sets of Mendelsohn triple systems with resolvability

open access: yesDiscrete Mathematics, 2013
Abstract An OLRMTS ( v ) ( OLARMTS ( v ) ) over a ( v + 1 ) -set X is a collection { ( X ∖ { x } , B x ) : x ∈ X } of v + 1 pairwise disjoint resolvable (almost resolvable) Mendelsohn triple systems of order v . In this paper several direct construction methods for
Junling Zhou, Yanxun Chang
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Symbolic Functional Calculus and N-Body Resolvent Estimates [PDF]

open access: yes, 2000
We construct a functional calculus for symbolic functions of “scattering pseudodifferential operators” on manifolds with boundary. This is applied to obtain mapping results on the scattering wavefront set of the B operator used by Gérard et al.
Hassell, Andrew, Vasy, András
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Maximal resolving sets in a graph

open access: yesInternational Journal of Mathematics for Industry
Let G be a connected graph. A subset [Formula: see text] of [Formula: see text] is called a resolving set of G if the code of any vertex [Formula: see text] with respect to S is different from the code of any other vertex where code of u with respect to S denoted by [Formula: see text] is defined as [Formula: see text].
V. Swaminathan, R. Sundareswaran
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Scattering Properties of Impulsive Discrete Dirac System with Hyperbolic Eigenparameter

open access: yesJournal of Mathematical Sciences and Modelling
In this work, we examine the spectral and scattering properties of an impulsive discrete Dirac system with hyperbolic parameter such as resolvent operator, the set of eigenvalues, Jost function, scattering solutions and scattering function.
Güler Başak Öznur
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Note on Property (gb) and Perturbations

open access: yesAbstract and Applied Analysis, 2012
An operator T∈ℬ(X) defined on a Banach space X satisfies property (gb) if the complement in the approximate point spectrum σa(T) of the upper semi-B-Weyl spectrum σSBF+-(T) coincides with the set Π(T) of all poles of the resolvent of T. In this paper, we
Qingping Zeng, Huaijie Zhong
doaj   +1 more source

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