Results 121 to 130 of about 870 (267)
On continuous and residual spectra of operators connected with iterative functional equations
Annales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2006 The sum type operator $F$, given by [ F lbrack varphi brack (x) : = displaystylesum^{infty}_{u = 0} 2^{-u} varphi (2^{u} x), ] will be considered on the space $D$ of bounded real functions, equipped with the supremum norm and on its ...
Hans-Heinrich Kairies
doaj
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Fixed Point Theory and Applications, 2010 A general nonlinear framework for an Ishikawa-hybrid proximal point algorithm using the notion of -accretive is developed. Convergence analysis for the algorithm of solving a nonlinear set-valued inclusions problem and existence analysis of solution ...
Jin MaoMing, Li HongGang, Xu AnJian
doaj
An analysis on the approximate controllability of neutral impulsive stochastic integrodifferential inclusions via resolvent operators. [PDF]
Heliyon, 2023 Ma YK +4 more
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Fixed Point Theory and Applications, 2010 The main purpose of this paper is to introduce and study a new class of generalized nonlinear set-valued quasi-variational inclusions system involving -accretive mappings in Banach spaces. By using the resolvent operator due to Lan-Cho-Verma associated
Jin MaoMing, Li Hong-Gang, Xu AnJian
doaj
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Systems of general nonlinear set-valued mixed variational inequalities problems in Hilbert spaces
Fixed Point Theory and Applications, 2011 In this paper, the existing theorems and methods for finding solutions of systems of general nonlinear set-valued mixed variational inequalities problems in Hilbert spaces are studied.
Cho Yeol, Petrot Narin, Agarwal Ravi
doaj