Results 141 to 150 of about 32,295 (236)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Generalized nonlinear mixed implicit quasi-variational inclusions with set-valued mappings
Journal of Inequalities and Applications, 2002 In this paper, we introduce and study a new class of implicit quasi-variational inclusions, which is called the generalized nonlinear mixed implicit quasi-variational inclusion with setvalued mappings.
Huang NJ, Cho YJ, Agarwal RP
doaj
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
On continuous and residual spectra of operators connected with iterative functional equations
Annales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2006 The sum type operator $F$, given by [ F lbrack varphi brack (x) : = displaystylesum^{infty}_{u = 0} 2^{-u} varphi (2^{u} x), ] will be considered on the space $D$ of bounded real functions, equipped with the supremum norm and on its ...
Hans-Heinrich Kairies
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Resolvent approaches to elliptic regularity in stationary Fokker–Planck equations
Demonstratio MathematicaThis paper investigates the local regularity of solutions to stationary Fokker–Planck equations on an open set U⊂Rd $U\subset {\mathbb{R}}^{d}$ with d ≥ 2.
Lee Haesung
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Fixed Point Theory and Applications, 2010 A general nonlinear framework for an Ishikawa-hybrid proximal point algorithm using the notion of -accretive is developed. Convergence analysis for the algorithm of solving a nonlinear set-valued inclusions problem and existence analysis of solution ...
Jin MaoMing, Li HongGang, Xu AnJian
doaj
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Fixed Point Theory and Applications, 2010 The main purpose of this paper is to introduce and study a new class of generalized nonlinear set-valued quasi-variational inclusions system involving -accretive mappings in Banach spaces. By using the resolvent operator due to Lan-Cho-Verma associated
Jin MaoMing, Li Hong-Gang, Xu AnJian
doaj