Results 131 to 140 of about 32,295 (236)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Gevrey estimates of the resolvent and sub-exponential time-decay of solutions

, 2017
In this article, we study a class of non-selfadjoint Schr{\"o}dinger operators H which are perturbation of some model operator H 0 satisfying a weighted coercive assumption.
Wang, Xue Ping
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Perturbed Iterative Algorithms for Generalized Nonlinear Set-Valued Quasivariational Inclusions Involving Generalized -Accretive Mappings

Journal of Inequalities and Applications, 2007
A new class of generalized nonlinear set-valued quasivariational inclusions involving generalized -accretive mappings in Banach spaces are studied, which included many variational inclusions studied by others in recent years.
Jin Mao-Ming
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Resolvent set of the M/MB/1 operator

Computers & Mathematics with Applications, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Some Results for Integral Inclusions of Volterra Type in Banach Spaces

Advances in Difference Equations, 2010
We first present several existence results and compactness of solutions set for the following Volterra type integral inclusions of the form: , where , is the infinitesimal generator of an integral resolvent family on a separable Banach space , and is ...
Nieto JJ, Benchohra M, Ouahab A, Agarwal RP   +3 more
doaj  

Hille–Yosida-Type Theorem for Fractional Differential Equations with Dzhrbashyan–Nersesyan Derivative

Fractal and Fractional
It is a well-known fact that the Dzhrbashyan–Nersesyan fractional derivative includes as particular cases the fractional derivatives of Riemann–Liouville, Gerasimov–Caputo, and Hilfer.
Vladimir E. Fedorov, Wei-Shih Du, Marko Kostić, Marina V. Plekhanova, Darya V. Melekhina   +4 more
doaj   +1 more source