Results 51 to 60 of about 5,753,342 (293)

Surface plasmon-coupled emission for applications in biomedical diagnostics [PDF]

open access: yes, 2009
Surface plasmon-coupled emission (SPCE) is a phenomenon whereby the light emitted from a fluorescent molecule can couple into the surface plasmon of an adjacent metal layer resulting in highly directional emission in the region of the surface plasmon ...
Trnavsky, Michal
core   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Fabrication and Characterization of Line-by-Line Inscribed Tilted Fiber Bragg Gratings Using Femtosecond Laser

open access: yesSensors, 2021
In this paper, we studied the basic characteristics of tilted fiber Bragg gratings (TFBGs), inscribed line-by-line. Experimental results showed that if the TFBGs were located within different planes parallel to the fiber axis, the spectra performed ...
Hongye Li   +5 more
doaj   +1 more source

The Effect of Flip Angle on the Accuracy and Repeatability of Hepatic Proton Density Fat Fraction Estimation by Complex data-based, T1-independent, T2*-corrected, Spectrum-Modeled Magnetic Resonance Imaging

open access: yesJournal of Magnetic Resonance Imaging, 2013
To evaluate the effect of flip angle (FA) on accuracy and within‐examination repeatability of hepatic proton‐density fat fraction (PDFF) estimation with complex data‐based magnetic resonance imaging (MRI).
B. Johnson   +10 more
semanticscholar   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Sensitivity-Enhanced SPR Sensor Based on Graphene and Subwavelength Silver Gratings

open access: yesNanomaterials, 2020
A novel surface plasmon resonance (SPR) sensor with graphene and subwavelength gratings is proposed to improve the sensing performance. A series of numerical analyses were performed to investigate the effect of structural parameters on the sensing ...
Lu Kong   +5 more
doaj   +1 more source

Portable Non-Destructive Magnetic Resonance Sensor for Assessing the Aging Status of Silicon Rubber Insulators

open access: yesNanomaterials, 2022
Silicone rubber insulators (SRIs) are widely used in high-voltage power grids. Due to high-voltage fields and harsh environmental conditions, SRIs eventually deteriorate with use in the power grid, decreasing their insulating performance and operational ...
Pan Guo   +4 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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