Results 141 to 150 of about 6,147 (304)

Quality evaluation of portland cement concrete at early age with Free -Free Resonant Column

open access: yes, 2008
At early age, the behavior and mechanical properties of portland cement concrete changes rapidly with time due to hydration. The hydration process consists of a series of chemical reactions that accelerate nonlinearly with the rise in temperature.
Wenglas, Gilberto   +1 more
core  

Sistema eletrônico para lâmpadas de vapor de sódio de alta pressão [PDF]

open access: yes, 2004
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Elétrica.O presente trabalho aborda o desenvolvimento e a implementação do protótipo de um reator eletrônico destinado à alimentação de
Andre, Anderson Soares
core  

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

open access: yesAdvanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda   +8 more
wiley   +1 more source

Proposed ASTM Standard for the Stokoe-type Resonant Column Torsional Shear Device

open access: yes, 2018
Resonant Column Torsional Shear (RCTS) testing has become one of the most commonly used methods for determining laboratory soil stiffness and soil damping.
Tran, Anh Tuan
core  

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

MEASURING DYNAMIC PROPERTIES OF WIND TURBINE FOUNDATION SOIL IN RESONANT COLUMN - ISSUES AND CHALLENGES

open access: yes, 2014
Wind turbine foundations are subject to large dynamic wind loads. The horizontal wind loads create large shear forces and moments on the foundation, which may result in critical issues related to the stability and deformation of wind turbine generator ...
WU, ZHENZHONG
core  

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

open access: yesAdvanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel   +16 more
wiley   +1 more source

Gas hydrate growth morphologies and their effect on the stiffness and damping of a hydrate bearing sand

open access: yes, 2008
Using a specially constructed Gas Hydrate Resonant Column (GHRC), the University of Southampton explored different methods of hydrate synthesis and measured the properties of the resulting sediments, such as shear wave velocity (Vs), compressional wave ...
Kingston, Emily   +4 more
core  

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

open access: yesAdvanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou   +22 more
wiley   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao   +11 more
wiley   +1 more source

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