Results 91 to 100 of about 208,794 (315)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Postdigital Science and EducationThe boundaries between the digital and the analog become increasingly blurred, our experiences are pluralized and datafied in a web of constant connectivity. This web fundamentally transforms our perception of the world, altering ‘our relationship to time and space, to other people, to the objects around us, and ultimately to ourselves, to our body and
Lawrence Wilde +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Double-Layer Crystalline Silicon on Insulator Material Platform for Integrated Photonic Applications
IEEE Photonics Journal, 2014 We report a high optical-quality double-layer silicon (Si) material platform with a thin interface oxide using a low-temperature wafer bonding technique.
Hesam Moradinejad +4 more
doaj +1 more source
Light: Science & Applications, 2016 Single-molecule detection is one of the fundamental challenges of modern biology. Such experiments often use labels that can be expensive, difficult to produce, and for small analytes, might perturb the molecular events being studied.
Judith Su +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Editorial: Resonance? Resonate! Artistic Research and the Need for Resonance
HUB - Journal of Research in Art, Design and SocietyResonance+ invites readers to continue the dialogue beyond the SAR 2025 Conference through contributions that explore resonance within artistic research. Some expand upon perspectives presented at SAR 2025, while others approach the theme independently, inspired by its ongoing relevance to artistic practice. keywords:
null Orlando Vieira Francisco +5 more
openaire +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
Light and sound interplay in whispering gallery mode resonators
Journal of the European Optical Society-Rapid PublicationsWhispering Gallery Mode Resonators (WGMRs) are robust and compact structures that confine resonant photons and phonons for extended time. This extraordinary confinement greatly enhances light and sound interactions and allows a plethora of fundamental ...
Frigenti Gabriele +6 more
doaj +1 more source