Results 81 to 90 of about 78,280 (298)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Polarization effects in microcoil resonators
, 2010 Optical microcoil resonators (OMRs), formed by coiling a micron-diameter fibre around a rod as shown in Figure 1a, provide a unique resonator geometry in which light can evanescently couple between adjacent turns to produce high Q resonances. Furthermore,
Broderick, N.G.R. +2 more
core +1 more source
All-Resonant Control of Superconducting Resonators
Physical Review Letters, 2012 4 + epsilon pages, plus supplemental ...
openaire +4 more sources
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Double-Layer Crystalline Silicon on Insulator Material Platform for Integrated Photonic Applications
IEEE Photonics Journal, 2014 We report a high optical-quality double-layer silicon (Si) material platform with a thin interface oxide using a low-temperature wafer bonding technique.
Hesam Moradinejad +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Computation of scattering resonances for dielectric resonators
Computers & Mathematics with Applications, 2010 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Polarisation effects in optical microcoil resonators
Optical microcoil resonators (OMRs) fabricated by wrapping a microfibre around a rod to allow evanescent coupling between adjacent turns as in Fig 1.
Brambilla, Gilberto +2 more
core +1 more source