Results 81 to 90 of about 90,838 (300)
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Polarisation effects in optical microcoil resonators
Optical microcoil resonators (OMRs) fabricated by wrapping a microfibre around a rod to allow evanescent coupling between adjacent turns as in Fig 1.
Brambilla, Gilberto +2 more
core +1 more source
TechnologiesIndustrial motors generate vibration energy that can be converted into electrical energy using piezoelectric vibration energy harvesters (pVEHs). These energy harvesters can power devices or function as self-powered sensors.
Moisés Vázquez-Toledo +5 more
doaj +1 more source
Computation of scattering resonances for dielectric resonators
Computers & Mathematics with Applications, 2010 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Novel compact substrate integrated waveguide resonators at 60 GHz for LCP [PDF]
, 2008 In this paper a new approach to design of compact substrate integrated resonators is presented. LCP substrate integrated waveguide is loaded by array of multilayer metallic plates situated inside the substrate.
Budimir, D. +2 more
core +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Nanophotonics, 2018 Currently, the reversible logic circuit is a popular research topic in the field of information processing as it is a most effective approach to minimize power consumption, which can achieve the one-to-one mapping function to identify the input signals ...
Tian Yonghui +10 more
doaj +1 more source
[Design and Investigation of a Hybrid Optical Resonator for Medium Energy COIL] [PDF]
, 2007 High brightness laser radiation of chemical oxygen iodine lasers (COIL) requires resonator types especially adapted to low gain medium and rectangular cavity geometry.
Grünewald, Karin +3 more
core