Results 51 to 60 of about 90,838 (300)
An improved simplified composite right‐/left‐handed (SCRLH) zeroth‐order resonator (ISZOR) is introduced, comprising two lateral parallel capacitors and a centred T‐type inductor circuit.
Yongchang Yu +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Cross-Linked Nanoparticle Membranes for Microelectromechanical Chemical Sensors and Pressure Sensors
We present novel microelectromechanical chemical sensors for the detection of volatile organic compounds based on electrostatically actuated, nanometer-thin, freestanding membranes of organically cross-linked gold nanoparticles.
Hendrik Schlicke +5 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
On-chip optical parity checker using silicon photonic integrated circuits
The optical parity checker plays an important role in error detection and correction for high-speed, large-capacity, complex digital optical communication networks, which can be employed to detect and correct the error bits by using a specific coding ...
Liu Zilong +9 more
doaj +1 more source
We present circular architecture bioimplant strain sensors that facilitate a strong resonance frequency shift with mechanical deformation. The clinical application area of these sensors is for in vivo assessment of bone fractures.
Hilmi Volkan Demir +4 more
doaj +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Mid-infrared whispering gallery resonators based on non-oxide nonlinear optical crystals
Paper 105180X, 6 S.High-quality whispering gallery resonators (WGRs) made of AgGaSe2 and CdSiP2 bulk crystals are fabricated. With femtosecond laser matching and subsequent fine polishing, the intrinsic Q-factors of these resonators are approaching ...
Buse, Karsten +5 more
core +1 more source

