Results 141 to 150 of about 2,581,993 (306)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Knowledge mobilization in healthcare organizations: a view from the resource-based view of the firm. [PDF]

open access: yesInt J Health Policy Manag, 2015
Ferlie E   +5 more
europepmc   +1 more source

Examining resource based view against transactional costs Approach in the french poultry industry : treading upon eggs.. [PDF]

open access: yes
France; Intégration verticale; Coûts de la transaction; French Poultry Industry; Aviculture;
Ghozzi, Houda
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Organising new product development Knowledge hollowing-out and knowledge integration [PDF]

open access: yes
The paper analyses the organization of the new product development process at FIAT from a resource-based perspective. The focus is on organizational resources for integrating dispersed specialist knowledge required in the development of complex products.
Francesco Zirpoli, Markus C. Becker
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

ESTRATÉGIAS COMPETITIVAS EM INSTITUIÇÕES DE ENSINO SUPERIOR: UM ESTUDO DE CASO À LUZ DA VISÃO BASEADA EM RECURSOS

open access: yesRevista Gestão Universitária na América Latina, 2017
This study sought to highlight the resources used by an institution of higher education in the pursuit of competitive advantage, based on the precepts of the resource - based view.
David Rodrigo Petry   +4 more
doaj  

Home - About - Disclaimer - Privacy