Results 131 to 140 of about 9,284,406 (331)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

A Remote Laser Mass Spectrometer for Lunar Resource Assessment [PDF]

open access: yes
The use of lasers as a source of excitation for surface mass spectroscopy has been investigated for some time. Since the laser can be focused to a small spot with intensity, it can vaporize and accelerate atoms of material.
Deyoung, R. J., Williams, M. D.
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Ocean wave energy resource assessment-- hotspots, exceedance-persistance, and predictability : a thesis presented in partial fulfilment of the requirements for the degree of Master of Applied Science in Natural Resource Engineering at Massey University [PDF]

open access: yes, 2007
Ocean wave energy conversion is evolving towards commercial viability. Succinct resource assessment is essential to the conversion of wave energy for grid supply electrical generation. The ability to differentiate potential wave energy locations by means
Frazerhurst, James Edward
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Economic Evaluation of Telemedicine Services Provided at Satellite Centre for Tribal Health and Research, Abu Road Sirohi Rajasthan India

open access: yesAsia Pacific Journal of Health Management
Background: Assessing health technology is a vital tool for determining whether interventions should be continued or stopped. Delivering efficient medical services in remote tribal, hilly regions demands careful planning to maximize limited resources ...
Amit Kumar Mittal   +6 more
doaj  

Geospatial mapping of groundwater potential for irrigated agriculture in semi-arid Kongwa District, Central Tanzania

open access: yesFrontiers in Water
Groundwater is vital for agriculture in semi-arid regions like Kongwa District, where surface water is scarce and rainfall unstable. Despite its significance, detailed knowledge on groundwater distribution in such areas is often lacking, hindering ...
Faida Zacharia   +2 more
doaj   +1 more source

Supporting Decisions: Understanding natural resource management assessment techniques [PDF]

open access: yes
Report to the Land and Water Resources Research and Development Corporation. This document presents a review of NRM decision support techniques. It draws upon previous studies in the fields of management science, operations research, environmental ...
Darla Hatton MacDonald   +2 more
core  

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