Results 71 to 80 of about 2,704,412 (312)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Ocean wave energy resource assessment-- hotspots, exceedance-persistance, and predictability : a thesis presented in partial fulfilment of the requirements for the degree of Master of Applied Science in Natural Resource Engineering at Massey University [PDF]

, 2007
Ocean wave energy conversion is evolving towards commercial viability. Succinct resource assessment is essential to the conversion of wave energy for grid supply electrical generation. The ability to differentiate potential wave energy locations by means
Frazerhurst, James Edward
core  

Economic Evaluation Plan (EEP) for A Very Early Rehabilitation Trial (AVERT): An international trial to compare the costs and cost-effectiveness of commencing out of bed standing and walking training (very early mobilization) within 24 h of stroke onset with usual stroke unit care [PDF]

, 2016
Rationale: A key objective of A Very Early Rehabilitation Trial is to determine if the intervention, very early mobilisation following stroke, is cost-effective.
Fiona Ellery, Helen Dewey, Janice M Collier, Julie Bernhardt, Kiu Tay-Teo, Lauren Sheppard, Leonid Churilov, Marj Moodie, null null, Olivia Wu   +9 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

An examination of the potential applications of automatic classification techniques to Georgia management problems [PDF]

Automatic classification techniques are described in relation to future information and natural resource planning systems with emphasis on application to Georgia resource management problems.
Rado, B. Q.
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Zircon U-Pb Geochronology and Uranium-Production Capacity of the Taoshan Complex in Southern Jiangxi

Yankuang ceshi, 2014
The Taoshan granite complex located at the North-East part of the Nanling region, hosts the largest granite-related uranuim ore field in China. Baohuashan granite and Huangpi granite are two major components of the Taoshan granite complex.
Tian zejin, Chen zhenyu, Wang denghong, Chen zhenghui, Huang fan, Zhao zheng, Hou kejun   +6 more
doaj   +2 more sources

A Hidden Pitfall for REDD: Analysis of Power Relation in Participatory Forest Management on Whether It Is an Obstacle or a Reliever on REDD Pathway

International Journal of Forestry Research, 2015
Power relation among stakeholders is a key concept in collaborative approaches. This study aims to examine the reality of the acclaimed power sharing in Participatory Forest Management (PFM) and implication of existing power relation to the national ...
Angelingis Akwilini Makatta, Faustin Peter Maganga, Amos Enock Majule   +2 more
doaj   +1 more source

Gender and development: bridging the gap between research and action [PDF]

Gender, Development, Research, households, Household resource allocation, Property rights, Project evaluation, Needs assessment,
McClafferty, Bonnie, Quisumbing, Agnes R.   +1 more
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