Results 11 to 20 of about 19,721 (245)

Whole-Transcriptome Analysis of Yak and Cattle Heart Tissues Reveals Regulatory Pathways Associated With High-Altitude Adaptation

Frontiers in Genetics, 2021
BackgroundThe yak (Bos grunniens) is an important livestock species that can survive the extremely cold, harsh, and oxygen-poor conditions of the Qinghai-Tibetan Plateau and provide meat, milk, and transportation for the Tibetans living there.
Hui Wang, Hui Wang, Jincheng Zhong, Jincheng Zhong, Jikun Wang, Jikun Wang, Zhixin Chai, Zhixin Chai, Chengfu Zhang, Jinwei Xin, Jiabo Wang, Jiabo Wang, Xin Cai, Xin Cai, Zhijuan Wu, Zhijuan Wu, Qiumei Ji   +16 more
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Establishment of a subcutaneous adipogenesis model and distinct roles of LKB1 regulation on adipocyte lipid accumulation in high-altitude Bos grunniens

Journal of Applied Animal Research, 2022
The domestic yak was regarded as a valuable model to explore the molecular mechanism of high-altitude animal adaptation, including the extreme tolerance of starvation and cold stress, which is closely associated with specifically seasonal deposition and ...
Yongqi Yue, Yonglin Hua, Jing Zhang, Yu Guo, Dan Zhao, Wentao Huo, Yan Xiong, Fenfen Chen, Yaqiu Lin, Xianrong Xiong, Jian Li   +10 more
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Single-cell transcriptome analysis and in vitro differentiation of testicular cells reveal novel insights into male sterility of the interspecific hybrid cattle-yak

BMC Genomics, 2023
Background Interspecific hybridization plays vital roles in enriching animal diversity, while male hybrid sterility (MHS) of the offspring commonly suffered from spermatogenic arrest constitutes the postzygotic reproductive isolation.
TserangDonko Mipam, Xuemei Chen, Wangsheng Zhao, Peng Zhang, Zhixin Chai, Binglin Yue, Hui Luo, Jikun Wang, Haibo Wang, Zhijuan Wu, Jiabo Wang, Mingxiu Wang, Hui Wang, Ming Zhang, Hongying Wang, Kemin Jing, Jincheng Zhong, Xin Cai   +17 more
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CIDEB promotes lipid deposition in goat intramuscular adipocytes [PDF]

Animal Bioscience
Objective Cell death-inducing DNA fragmentation factor alpha-like effector B (CIDEB), a family member of Cell death-inducing DFF45-like effectors (CIDEs), is well known as a crucial regulator for lipid metabolic signaling pathways in various metabolic ...
Zhuohan Huang, Qi Li, Changheng Yang, Changhui Zhang, Lian Huang, Yaqiu Lin, Yong Wang, Hua Xiang, Jiangjiang Zhu   +8 more
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KLF4 Inhibits the Differentiation of Goat Intramuscular Preadipocytes Through Targeting C/EBPβ Directly

Frontiers in Genetics, 2021
Intramuscular fat (IMF) deposition is a complicated process, and most of the underlying regulators of this biological process are unknown. Here, we cloned the intact CDS of KLF4 gene, investigated the role of KLF4 by gaining or losing function in vitro ...
Qing Xu, Qing Xu, Qing Xu, Yanyan Li, Yanyan Li, Sen Lin, Sen Lin, Yong Wang, Yong Wang, Yong Wang, Jiangjiang Zhu, Jiangjiang Zhu, Yaqiu Lin, Yaqiu Lin, Yaqiu Lin   +14 more
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Chi-circ_0009659 modulates goat intramuscular adipocyte differentiation through miR-3431-5p/STEAP4 axis [PDF]

Animal Bioscience
Objective Circular RNAs (circRNAs) are widely involved in the regulation of lipid deposition in animals, but there are few reports on key circRNAs regulating intramuscular adipocyte differentiation in goats.
Xin Li, Hao Zhang, Yong Wang, Yanyan Li, Youli Wang, Yan Xiong, Wei Liu, Yaqiu Lin   +7 more
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Molecular Regulation of Yak Preadipocyte Differentiation and Proliferation by LncFAM200B and ceRNA Regulatory Network Analysis

Cells, 2022
The positive regulatory role of lncFAM200B in differentiation and lipid deposition in yak intramuscular preadipocytes has been demonstrated in our previous study. However, the regulatory mechanisms remain unclear.
Hongbiao Ran, Youzhualamu Yang, Mengning Luo, Xinrui Liu, Binglin Yue, Zhixin Chai, Jincheng Zhong, Hui Wang   +7 more
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MiR-196a Promotes Lipid Deposition in Goat Intramuscular Preadipocytes by Targeting MAP3K1 and Activating PI3K-Akt Pathway

Cells
Meat quality in goats is partly determined by the intramuscular fat (IMF) content, which is associated with the proliferation and differentiation of intramuscular preadipocytes. Emerging studies have suggested that miRNA plays a crucial role in adipocyte
Yuling Yang, Wenyang Zhang, Haiyang Li, Hua Xiang, Changhui Zhang, Zhanyu Du, Lian Huang, Jiangjiang Zhu   +7 more
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Expression, Purification, and Characteristic of Tibetan Sheep Breast Lysozyme Using Expression System [PDF]

Asian-Australasian Journal of Animal Sciences, 2014
A lysozyme gene from breast of Tibetan sheep was successfully expressed by secretion using a-factor signal sequence in the methylotrophic yeast, Pichia pastoris GS115.
Jianbo Li, Mingfeng Jiang, Yong Wang
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miR-214-5p Regulating Differentiation of Intramuscular Preadipocytes in Goats via Targeting KLF12

Frontiers in Genetics, 2021
Intramuscular fat (i.m.) is an adipose tissue that is deposited between muscle bundles. An important type of post-transcriptional regulatory factor, miRNAs, has been observed as an important regulator that can regulate gene expression and cell ...
Yu Du, Yu Du, Yong Wang, Yong Wang, Yong Wang, Yanyan Li, Yanyan Li, Yanyan Li, Quzhe Emu, Jiangjiang Zhu, Jiangjiang Zhu, Yaqiu Lin, Yaqiu Lin, Yaqiu Lin   +13 more
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