Results 81 to 90 of about 3,918,502 (296)
Journal of the Medical Library Association, 2018 LiveStories is a web-based storytelling platform that is equipped with interactive data visualization tools, drag-and-drop publishing, and its own public data library.
Kelli Yakabu, Andrea Ball
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Using Large Language Models to Address Contextual Questions in Systematic Reviews
Cochrane Evidence Synthesis and MethodsObjectives Systematic evidence reviews (SERs) produced by the U.S. Agency for Healthcare Research and Quality (AHRQ) Evidence‐based Practice Center (EPC) Program use contextual questions to provide context and background information on the topic.
Susanne Hempel +7 more
doaj +1 more source
Journal of the Medical Library Association, 2018 5MinuteConsult is an online resource that is designed to help health care professionals and clinical students make evidence-based decisions by providing information that is needed at the point-of-car.
Ivan Armando Portillo
doaj +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Journal of the Medical Library Association, 2018 Many clinical libraries offer a journal alerting service that gives clinicians the opportunity to review the most current tables of contents for journals of interest.
Rob Penfold
doaj +1 more source
Resource management for Sustainable Development of Island Economies [PDF]
What is the role of resource management in sustaining competitiveness for island economies such as the Republic of the Philippines and Hawaii? We review the history of thought on sustainable resource management and sustainable development and then turn ...
James Roumasset +2 more
core
, 2008 The spatio-temporal dynamics of a population present one of the most fascinating aspects and challenges for ecological modelling. In this article we review some simple mathematical models, based on one dimensional reaction-diffusion-advection equations ...
Blasius, B., Ryabov, A. B.
core +1 more source
Economic evidence for the prevention and treatment of atopic eczema: a protocol for a systematic review [PDF]
, 2016 Background: Eczema, synonymous with atopic eczema or atopic dermatitis, is a chronic skin disease that has a similar impact on health-related quality of life as other chronic diseases.
AS Paller +18 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source