Results 91 to 100 of about 1,558,704 (279)

Raptor resource use in agroecosystems: cover crops and definitions of availability matter

open access: yesAvian Conservation and Ecology, 2021
The populations of many species of raptors that forage in agroecosystems have declined as agriculture has intensified. Cover crops are a recent trend in areas of intensive row-crop agriculture in the Midwestern United States that could positively affect
Megan E. Zagorski, Robert K. Swihart
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Reputation and Competence in Publicly Funded Science: Estimating the Effects on Research Group Productivity.. [PDF]

open access: yes
This paper estimates the "production function" for scientific research publications in the field of biotechnology. It utilizes an exceptionally rich and comprehensive data set pertaining to the universe of research groups that applied to a 1989-1993 ...
Arora, Ashish   +2 more
core   +1 more source

Q-CAD: QoS and Context Aware Discovery framework for adaptive mobile systems [PDF]

open access: yes, 2005
This paper presents Q-CALl, a resource discovery framework that enables pervasive computing applications to discover and select the resource(s) best satisfying the user needs, taking the current execution context and quality-ofservice (QoS ...
Capra, L., Mascolo, C., Zachariadis, S.
core   +4 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Conditioning the logistic branching process on non-extinction

open access: yes, 2013
We consider a birth and death process in which death is due to both `natural death' and to competition between individuals, modelled as a quadratic function of population size.
Etheridge, Alison   +2 more
core  

Evaluation of the Children’s Commissioning Support Resource. Final report [PDF]

open access: yes, 2012
It is clear that the CCSR has not fully realised its initial goals and there are a range of factors preventing it from doing so. - The interlinked nature of the issues influencing its success means that it is difficult at this stage to set a specific ...
Cowen, Georgina
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

A reformulation of the selection ratio shed light on resource selection functions and leads to a unified framework for habitat selection studies [PDF]

open access: yes, 2019
Abstract The selection ratio (SR), i.e. the ratio of proportional use of a habitat over proportional availability of this habitat, has for long been the standard metric of habitat selection analyses. It is easy to compute and directly estimates disproportionate use.
openaire   +1 more source

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