Results 91 to 100 of about 335,691 (302)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Dynamic UL/DL Mode Selection and Resource Allocation in Multi-Cell MIMO TDD Systems [PDF]

open access: yes, 2019
This paper considers joint uplink/downlink mode selection and resource allocation problem in multi-cell systems for flexible TDD frame structures. To combat the difficult interference characteristics of such systems, a dynamic mode selection and resource
Arvola, Antti   +5 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Assessing Ecological Connectivity for Loxodonta africana Across Transfrontier Conservation Areas in Southern Mozambique

open access: yesEcology and Evolution
Biodiversity loss driven by habitat degradation and fragmentation poses a critical threat to global ecosystems and demands conservation strategies that go beyond isolated protected areas. We assessed the functional connectivity of African bush elephants (
Francesca Romana Trezza   +15 more
doaj   +1 more source

cjlortie/Resource_selection_function_app: A resource selection app for animals in deserts

open access: yes, 2019
An app to examine different key drivers on resource selection function for an endangered ...
Christopher J Lortie
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Integrating individual tracking data and spatial surveys to improve estimation of animal spatial distribution

open access: yesEcosphere
Tracking data and spatial surveys (e.g., counts) contribute to understanding animal distribution despite highlighting complementary aspects of habitat selection, from detailed insights on few individuals to raw inferences for the population, respectively.
Valentin Lauret   +3 more
doaj   +1 more source

An intelligent radio access network selection and optimisation system in heterogeneous communication environments

open access: yes, 2010
PhDThe overlapping of the different wireless network technologies creates heterogeneous communication environments. Future mobile communication system considers the technological and operational services of heterogeneous communication environments. Based
Luo, Weizhi
core  

Orangutans adjust resource selection over time after release.

open access: yes, 2019
Relative probability of selection in 32 orangutans (n = 13 females, n = 19 males) as a function of time after release (six different scenarios, in days) interacted with the distance to the FZS station (a, in meters), and elevation (b, in meters).
Doris Kelle (6655262)   +5 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

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