Results 71 to 80 of about 335,691 (302)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Joint Client Selection and CPU Frequency Control in Wireless Federated Learning Networks with Power Constraints

open access: yesEntropy, 2023
Federated learning (FL) represents a distributed machine learning approach that eliminates the necessity of transmitting privacy-sensitive local training samples.
Zhaohui Zhou   +4 more
doaj   +1 more source

Emergence of Function and Selection from Recursively Programmed Polymerisation Reactions in Mineral Environments

open access: yes, 2019
Living systems are characterised by an ability to sustain chemical reaction networks far-from-equilibrium. It is likely that life first arose through a process of continual disruption of equilibrium states in recursive reaction networks, driven by ...
David, Doran   +2 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Invasion of annual grasses following wildfire corresponds to maladaptive habitat selection by a sagebrush ecosystem indicator species

open access: yesGlobal Ecology and Conservation, 2022
Numerous wildlife species within semi-arid shrubland ecosystems across western North America are experiencing substantial habitat loss and fragmentation.
Brianne E. Brussee   +8 more
doaj   +1 more source

Temporal variation and scale in movement-based resource selection functions

open access: yesStatistical Methodology, 2014
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Hooten, M. B.   +3 more
openaire   +3 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Across scales, pronghorn select sagebrush, avoid fences, and show negative responses to anthropogenic features in winter

open access: yesEcosphere, 2019
Pronghorn (Antilocapra americana) are endemic to western North America where they occupy expanses of grassland and sagebrush (Artemisia spp.) habitats.
Adele K. Reinking   +4 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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