Results 91 to 100 of about 15,653,492 (359)

Non-seismic geophysical analysis of potential geothermal resources in the Longgang Block, Northeast China

open access: gold, 2022
Haiyan Liu   +5 more
openalex   +1 more source

Leadership Matters: Governors' Pre-K Proposals Fiscal Year 2006 [PDF]

open access: yes, 2005
Twenty budget-savvy governors recently recommended increased investment in a cost-effective strategy that saves taxpayers money, boosts state economies, and prepares our youngest citizens for future success.
Jennifer V. Doctors, L. Carol Scott
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

The Greater Boston Housing Report Card 2003: An Assessment of Progress on Housing in the Greater Boston Area [PDF]

open access: yes, 2004
Presents an annual survey of the state of housing in Greater Boston: market conditions; housing production; rents, home prices, and affordability; and public spending and support.
Barry Bluestone, Bonnie Heudorfer
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Sustainable dance making: Dancers and choreographers in collaboration [PDF]

open access: yes, 2008
In this paper I explore the notion of sustainability, drawing from environmental policy and activism, and apply this notion to the process of dance making.
Barbour, Karen
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Creating Change through Arts, Culture, and Equitable Development: A Policy and Practice Primer [PDF]

open access: yes, 2017
Across the nation, artistic and cultural practices are helping to define the sustainability of urban, rural, and suburban neighborhoods. In the design of parks and open spaces; the building of public transit, housing, and supermarkets; in plans for ...
Jeremy Liu   +2 more
core   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

PROJECT MANAGEMENT AND RESOURCE ALLOCATION OPTIMIZATION IN CONDITIONS CHARACTERIZED BY RISK [PDF]

open access: yesAnnals: Series on engineering sciences (Academy of Romanian Scientists), 2013
Project management represents the transformation of a vision into reality. The vision is a future state which put into practice will help up improve the company’s performance, solve a problem or exploit an opportunity for a higher profit.
Andrei-Stelian ZIDARU
doaj  

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