Results 71 to 80 of about 6,398,613 (281)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Resource Logics with a Diminishing Resource
International Joint Conference on Autonomous Agents and Multiagent Systems, 2018 Model-checking resource logics with production and consumption of resources is a computationally hard and often undecidable problem. We show that it is more feasible under the assumption that there is at least one diminishing resource , that is, a resource which is consumed by every action.
Natasha Alechina, Brian Logan 0001
openaire +3 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Water resources programs in Virginia
, 1966 Held Oct. 6-7, 1966, Richmond, Va. Sponsored by Water Resources Research Center, Virginia Polytechnic InstituteIncludes the papers presented at the symposium and reports by the Division of Mineral Resources and by the U.S.
core
PROJECT MANAGEMENT AND RESOURCE ALLOCATION OPTIMIZATION IN CONDITIONS CHARACTERIZED BY RISK [PDF]
Annals: Series on engineering sciences (Academy of Romanian Scientists), 2013 Project management represents the transformation of a vision into reality. The vision is a future state which put into practice will help up improve the company’s performance, solve a problem or exploit an opportunity for a higher profit.
Andrei-Stelian ZIDARU
doaj
The Economics of Resources or the Resources of Economics [PDF]
Journal of Natural Resources Policy Research, 1974 It is easy to choose a subject for a distinguished lecture like this, before a large and critical audience with a wide range of interests. You need a topic that is absolutely contemporary, but somehow perennial. It should survey a broad field, without being superficial or vague. It should probably bear some relation to economic policy, but of course it
openaire +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Organizational Arrangements for Developing Long-Range Water Resources Plans for Georgia
, 1989 Proceedings of the 1989 Georgia Water Resources Conference, May 16-17, 1989, Athens, Georgia.The Georgia Department of Natural Resources (DNR) has developed a state water plan, introduced by Governor Harris, which calls for the state to construct 12 ...
Hatcher, Kathryn J.
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source