Results 91 to 100 of about 6,398,613 (281)

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Herland Voice : v.29: no.1(2011)

open access: yes, 2011
The Herland Voice is the monthly publication of Herland Sister Resources, a womanist organization with a strong lesbian focus based in Oklahoma ...
Herland Sister Resources
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Herland Voice : v.29: no.3(2011)

open access: yes, 2011
The Herland Voice is the monthly publication of Herland Sister Resources, a womanist organization with a strong lesbian focus based in Oklahoma ...
Herland Sister Resources
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Annual report (Online); Division of Mineral Resources Management annual report

open access: yes, 2006
Annual; Electronic coverage as of Jan. 31, 2011: 2005-; Ohio Department of Natural Resources, Division of Mineral Resources Management is a result of the merger of Ohio Department of Natural Resources, Division of Mines and Reclamation, and Ohio ...
Ohio. Division of Mineral Resources Management.
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

FINANCING THE MILITARY HEALTH SYSTEM [PDF]

open access: yesAnnals: Series on Military Sciences, 2018
Health systems in EU Member States are funded through public contributions or direct contributions. Each Member State has developed its own funding mechanisms.
Gabriel COJOCARU
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Mineral resources: Geological scarcity, market price trends, and future generations

open access: yes, 2016
The extractable ores of the world's geologically scarcest mineral resources (e.g. antimony, molybdenum and zinc) may be exhausted within several decades to a century, if their extraction continues to increase.
Henckens, M.L.C.M.   +6 more
core   +1 more source

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