Results 91 to 100 of about 8,161,434 (267)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Herland Sister Resources : v.1: no.5(1985) [PDF]
, 1985 The Herland Sister Resources newsletter is the monthly publication of Herland Sister Resources, a womanist organization with a strong lesbian focus based in Oklahoma ...
Herland Sister Resources
core
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Herland Sister Resources : v.1: no.3(1985) [PDF]
, 1985 The Herland Sister Resources newsletter is the monthly publication of Herland Sister Resources, a womanist organization with a strong lesbian focus based in Oklahoma ...
Herland Sister Resources
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Herland Sister Resources : v.1: no.11(1985) [PDF]
, 1985 The Herland Sister Resources newsletter is the monthly publication of Herland Sister Resources, a womanist organization with a strong lesbian focus based in Oklahoma ...
Herland Sister Resources
core
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Herland Sister Resources : v.1: no.6(1985) [PDF]
, 1985 The Herland Sister Resources newsletter is the monthly publication of Herland Sister Resources, a womanist organization with a strong lesbian focus based in Oklahoma ...
Herland Sister Resources
core
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Annual report (Online); Division of Mineral Resources Management annual report
Annual; Description based on: 2004; title from PDF cover (viewed Dec. 12, 2006).; Ohio Department of Natural Resources, Division of Mineral Resources Management is a result of the merger of Ohio Department of Natural Resources, Division of Mines and ...
Ohio. Division of Mineral Resources Management.
core +1 more source