Results 101 to 110 of about 6,398,613 (281)

Elements of tourist destinations: Example of Tourist-recreation centre in Koštunići [PDF]

open access: yesZbornik Radova: Geografski Fakultet Univerziteta u Beogradu, 2016
There are various classifications of elements of tourist destinations in the scientific literature. For optimal consideration of elements of tourist destinations, the World Tourist Destination has proposed the FAS methodology applicable to the rural ...
Pavlović Sanja
doaj  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Water resources research activities under public law 88-379, fiscal year 1966

open access: yes, 1966
Submitted to the Director, Office of Water Resources ...

core  

Agricultural Law

open access: yesEDIS, 2003
Creation of the Environmental Protection Agency in 1970 brought with it a number of new and amended pre-existing environmental laws designed to monitor and regulate agricultural production practices.
Center for Natural Resources   +2 more
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Coolidge Regional Park Project

open access: yes, 1975
Published in cooperation with Arizona Water Commission and Office of Arid Lands Studies, University of Arizona.This item is part of the Water Resources Research Center collection.
McConnell, Carla L.   +3 more
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

A Five-Year Plan for Water Resources Research in Arizona

open access: yes, 1980
This item is part of the Water Resources Research Center collection. It was digitized from a physical copy provided by the Water Resources Research Center at The University of Arizona.
Water Resources Research Center. University of Arizona.
core  

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