Results 61 to 70 of about 2,301,842 (265)

Ethics in organization management

open access: yesJournal of Modern Science, 2018
You can have knowledge while learning ethics; which is moral and correct, but one can not learn a just course that would meet generally accepted norms. The fact is that it is much more difficult to evaluate the behavior according to the adopted standards,
Jerzy Tomasz Zawisza
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The syntactic features and emotional impact of Xitsonga interjections

open access: yesLiterator
The syntactic features and emotional impacts of interjections in Xitsonga have been largely overlooked in existing literature. This article aims to close this gap by exploring these aspects.
Respect Mlambo, Madala C. Hlungwani
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Evaluating the effectiveness of Xitsonga named entity recognition

open access: yesCogent Arts & Humanities
The development of robust Named Entity Recognition (NER) systems for African languages such as Xitsonga remains constrained by limited data availability, complex morphological structures, and orthographic variation.
Kulani Excellent Mhlongo, Respect Mlambo
doaj   +1 more source

RESPECT FOR DRUGS. [PDF]

open access: yesThe Lancet, 1904
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openaire   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Respecting Choices

open access: yesVoices in Bioethics, 2014
Voices in Bioethics, Archives (2014-2015)
openaire   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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