Results 91 to 100 of about 902,650 (342)
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
Currently, accessible objective indicators for predicting the prognosis and treatment outcomes of non-small cell lung cancer (NSCLC) are lacking. This study investigates the potential of T lymphocyte subsets and mitochondrial biomarkers as predictors of ...
Zhengming Huang, Chiqing Ying, Dan Zhu
doaj +1 more source
Living roots magnify the response of soil organic carbon decomposition to temperature in temperate grassland. [PDF]
Increasing atmospheric carbon dioxide (CO2) concentration is both a strong driver of primary productivity and widely believed to be the principal cause of recent increases in global temperature.
Farrar, J. +3 more
core +1 more source
The Effect of Respiration, pH, and Citrate Co-Metabolism on the Growth, Metabolite Production and Enzymatic Activities of Leuconostoc mesenteroides subsp. cremoris E30 [PDF]
Annamaria Ricciardi +4 more
openalex +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
The contribution of immunoregulatory cytokines to the formation of cold airway hyperresponsiveness in asthma patients is important for understanding approaches to therapy. Aim of the study was to investigate the interaction of tumor necrosis factor-alpha
A. B. Pirogov +3 more
doaj +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Laryngeal Nerve Activity During Pulse Emission in the CF-FM Bat, Rhinolophus ferrumequinum. II. The Recurrent Laryngeal Nerve [PDF]
The activity of the recurrent laryngeal nerve (RLN) was recorded in the greater horseshoe bat,Rhinolophus ferrumequinum. Respiration, vocalization and nerve discharges were monitored while vocalizations were elicted by stimulation of the central gray ...
Rübsamen, R., Schuller, Gerd
core +1 more source

