Results 231 to 240 of about 1,571,300 (298)

Redox-Dependent Modulation of Cardiac Mitochondrial F₁F_O-ATPase and Respiratory Function by N-Acetylcysteine and Sodium Ascorbate. [PDF]

Biology (Basel)
Cugliari A, Algieri C, Glogowski PA, Trombetti F, Buscaroli S, Fabbri M, Federici E, Nesci S.   +7 more
europepmc   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

Non-Mammalian Models for Mitochondria Research in CNS Disorders. [PDF]

Biomolecules
Svob Strac D, Filic V, Filosevic Vujnovic A, Vrhovac Madunic I, Madunic J, Cipak Gasparovic A, Havelka Mestrovic A, Andretic Waldowski R.   +7 more
europepmc   +1 more source

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

Advanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang, Jian‐Tong Shen, Hua‐Hua Zhang, Si‐Qi Gao, Ji‐Ao Wang, Yue‐Ling Wang, Mei‐Ling Li, Zi‐Meng Liu, Yi‐Nan Zhang, Yan Li, Xu‐Yu Zhang   +10 more
wiley   +1 more source

Copper Nanoparticles Enable Multi-Compartment Cuproenzyme Metalation in Cellular Models of Copper Deficiency. [PDF]

ACS Chem Biol
Kaur H, Soukar J, Gudekar N, Shanbhag VC, Petris MJ, Gaharwar AK, Gohil VM.   +6 more
europepmc   +1 more source

Cardiopulmonary Effects of Vagus Nerve Stimulation in Mice. [PDF]

eNeuro
Phillips CD, Driskill CM, Rajendran M, Krishnan DG, Kroener S, Thorn CA.   +5 more
europepmc   +1 more source

Neural and autonomic regulation during brief mindfulness and relaxation interventions in clinical populations: a multimodal MEG study protocol. [PDF]

Front Neurosci
Diny S, Schmidt F, Wutz A, Weisz N, Probst T.   +4 more
europepmc   +1 more source

Role of Astrocytes in Central Respiratory Control. [PDF]

Cells
Okada Y, Fukushi I, Yokota S, Takeda K, Umeda A, Pokorski M, Onimaru H.   +6 more
europepmc   +1 more source