Results 81 to 90 of about 3,346,625 (362)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Voice therapy with a respiratory approach in older people: an integrative literature review

Revista CEFAC, 2022
Purpose: to characterize voice therapy with a respiratory approach in dysphonic older people. Methods: a search made in PubMed, VHL, Scopus, Web of Science, and EMBASE.
Rebeca Lins de Souza Leão, Adriana de Oliveira Camargo Gomes, Mariana Rebeka Gomes Queiroz, Jonia Alves Lucena   +3 more
doaj   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Translation and cross-cultural adaptation of the self evaluation of breathing questionnaire (SEBQ) into Danish

European Clinical Respiratory Journal
Background and Purpose Dysfunctional breathing (DB) with or without an underlying medical condition is associated with impaired quality of life. DB-related symptoms can be measured with the 25-item Self Evaluation of Breathing Questionnaire (SEBQ ...
Karen Hjerrild Andreasson, Julie Sandell Jacobsen, Anja Leth Egsgaard, Kate Rauff Denby, Charlotte Hyldgaard, Uffe Bodtger, Charlotte Suppli Ulrik, Lone Schaadt, Rosalba Courtney, Anne Mette Schmidt   +9 more
doaj   +1 more source

Inspiratory Myoclonus

Tremor and Other Hyperkinetic Movements, 2019
Background: Movement disorders of respiration are rare and are restricted to a phase of the respiratory cycle. Phenomenology Shown: The intermittent inspiratory myoclonus in this patient with post-anoxic encephalopathy is likely to be of brainstem ...
Marieke C. J. Dekker, Kajiru G. Kilonzo, William P. Howlett, Mark Guttman, Esther Cubo   +4 more
doaj   +1 more source

Regulation of Mitochondrial Respiration by VDAC Is Enhanced by Membrane-Bound Inhibitors with Disordered Polyanionic C-Terminal Domains [PDF]

, 2021
Tatiana K. Rostovtseva, Sergey M. Bezrukov, David P. Hoogerheide   +2 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Nursing diagnoses and hospital readmission of patients with respiratory diseases: Findings from a case–control study

Nursing Open
Aim The rate of readmission after hospitalisation for respiratory diseases has become a common and challenging clinical problem. Social and functional patient variables could help identify cases at high risk of readmission.
Paloma Suárez‐González, Ane Suárez‐Elosegui, Lucía Arias‐Fernández, Irene Pérez‐Regueiro, Francisco J. Jimeno‐Demuth, Alberto Lana   +5 more
doaj   +1 more source

The Contribution of Iron to Protein Aggregation Disorders in the Central Nervous System

Frontiers in Neuroscience, 2019
The homeostasis of iron is of fundamental importance in the central nervous system (CNS) to ensure biological processes such as oxygen transport, mitochondrial respiration or myelin synthesis.
Karina Joppe, Anna-Elisa Roser, F. Maass, P. Lingor   +3 more
semanticscholar   +1 more source

Emerging functions of mammalian mitochondrial fusion and fission [PDF]

, 2005
Mitochondria provide a myriad of services to the cell, including energy production, calcium buffering and regulation of apoptosis. How these diverse functions are coordinated among the hundreds of mitochondria in a given cell is largely unknown, but is ...
Chan, David C., Chen, Hsiuchen
core   +1 more source