Results 121 to 130 of about 1,167,422 (304)

ATAD3 duplications bridge mitochondrial diseases and Aicardi–Goutières syndrome

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
ATAD3 locus duplications cause a severe neonatal mitochondrial disorder with neuroimaging features resembling interferonopathies, and suggest a mitochondrial nucleic acid‐triggered interferon response. Abstract A recurrent 68‐kb heterozygous duplication of the ATAD3 locus has been implicated in a mitochondrial disorder characterized by prenatal or ...
Pauline Planté‐Bordeneuve   +26 more
wiley   +1 more source

Ketosis and ketoacidosis in hospitalized patients receiving SGLT2 inhibitor therapy

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims The use and safety of sodium‐glucose co‐transporter 2 inhibitors (SGLT2i) in hospital are controversial due to the risk of ketoacidosis. We aimed to describe rates of ketosis, ketoacidosis, and acidosis in patients with type 2 diabetes treated with in‐hospital SGLT2i use.
Frank M. Gao   +8 more
wiley   +1 more source

Cortical hemodynamics of electrographic status epilepticus in the critically ill

open access: yesEpilepsia, Volume 66, Issue 3, Page 802-816, March 2025.
Abstract Objectives The pathophysiological mechanisms of status epilepticus (SE) underlying potential brain injury remain largely unclear. This study aims to employ functional near‐infrared spectroscopy (fNIRS) combined with video‐electroencephalography (vEEG) to monitor brain hemodynamics continuously and non‐invasively in critically ill adult ...
Ali Kassab   +6 more
wiley   +1 more source

Status epilepticus in older adults: A critical review

open access: yesEpilepsia, EarlyView.
Abstract Older adults (≥60 years of age) have the highest incidence of status epilepticus (SE) among adults and experience the highest morbidity and mortality. SE incidence increases with age in adulthood. A recent study from Austria estimated an incidence of 89.6/100 000 and 67.6/100 000 person‐years adjusted for age and sex in women and men aged >60 ...
Matthew R. Woodward   +5 more
wiley   +1 more source

Equine botulism

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik   +2 more
wiley   +1 more source

Adverse Outcomes and Associated Factors Among Children and Youths With Diabetes Mellitus in East Africa: A Systematic Review and Meta‐Analysis

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To identify adverse outcomes and factors associated with diabetes mellitus among children and youths in East Africa. Design This review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines.
Chalie Marew Tiruneh   +3 more
wiley   +1 more source

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