Brain strain: Blood flow and metabolism in environmental extremes
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak +3 more
wiley +1 more source
Abstract Menopause increases coronary heart disease risk, in part through reduced oestrogen‐mediated nitric oxide (NO) bioavailability. The Buckberg ratio, an index of myocardial oxygen supply–demand balance, in which higher values reflect more favourable myocardial perfusion, is lower in postmenopausal females (PMFs) than in age‐matched males.
Cassandra C. Derella +6 more
wiley +1 more source
Delayed Emergence Due to Severe Respiratory Acidosis Following Prolonged Spine Surgery: A Case Report. [PDF]
Khan IA, Tiwari JP.
europepmc +1 more source
Depiction of Delirium in Contemporary Medical Television Dramas: A Descriptive Content Analysis
Journal of the American Geriatrics Society, EarlyView.
Morgan Guest +5 more
wiley +1 more source
Abstract High‐altitude chronic hypoxia can induce excessive erythrocytosis (EE, defined as a haemoglobin concentration of ≥21 g/dL in men), leading to hyperviscosity and promoting endothelial dysfunction. We aimed to assess whether EE affects the retinal vascular phenotype and the ophthalmological vascular response to CO2.
Aymeric Paillisser +12 more
wiley +1 more source
Abstract figure legend During 10 h exposures to normobaric hypoxia exposure there was a selective leftward shift in ventilatory response to hyperoxic hypercapnic rebreathing, but not the cerebrovascular response. The key findings are that the resetting of the central chemoreflex to lower PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$ during early hypoxic ...
Holly Barclay +3 more
wiley +1 more source
Assessment of Conventional Oxygen Therapy, High-Flow Nasal Cannula, and Non-Invasive Ventilation to Secure Bronchofiberoscopy in Patients with Respiratory Acidosis: A Narrative Review and a Proposal for a Protocol in View of a Randomized Multicenter Study. [PDF]
Rycerski M +10 more
europepmc +1 more source
Neuromuscular fatigability with repeated exercise in hypoxia: From single‐joint paradigms to sprints
Abstract figure legend Acute hypobaric or normobaric hypoxic exposure accelerates neuromuscular fatigability during repeated exercise. Indices of peripheral and central fatigue are not different at exhaustion in mild, moderate and severe hypoxia compared with normoxia, but task failure occurs earlier.
Luca Ruggiero +5 more
wiley +1 more source
Severe Respiratory Acidosis-induced Involuntary Hyper defecation: The Role of Medullary Caudal Raphe Nuclei. [PDF]
Khandelwal A +3 more
europepmc +1 more source
Cardiovascular effects of intravenous colforsin in normal and acute respiratory acidosis canine models: A dose-response study. [PDF]
Itami T +5 more
europepmc +1 more source

