Results 161 to 170 of about 1,167,422 (304)

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich   +5 more
wiley   +1 more source

Case Report: Unusual Neurological Features of Leigh Syndrome due to m.8993T>G Pathogenic Variant in the MT‐ATP6 Gene

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 9, September 2025.
ABSTRACT The MT‐ATP6 gene m.8993T>G pathogenic variant has been associated with Leigh syndrome, especially in patients exhibiting a high degree of heteroplasmy. Although patients may present with a wide phenotypic spectrum, characteristic findings include bilateral, symmetric hyperintensities in the basal ganglia and brainstem on brain MRI ...
Ramya Treitel   +2 more
wiley   +1 more source

3D virtual biopsy of in vivo pH and metabolism using PRESS and semi‐LASER MRS of hyperpolarized 13C nuclei

open access: yesMagnetic Resonance in Medicine, Volume 94, Issue 3, Page 880-894, September 2025.
Abstract Purpose To develop and evaluate sequences for multi‐voxel magnetic resonance spectroscopy using hyperpolarized molecules. Methods A standard single voxel PRESS sequence was extended to acquire multiple voxels consecutively. Its SNR was compared against a 2D FID‐CSI with both 1H and hyperpolarized 13C nuclei in phantoms and in a healthy mouse ...
Wolfgang Gottwald   +11 more
wiley   +1 more source

Aminopyridines Restore Ventilation and Reverse Respiratory Acidosis at Late Stages of Botulism in Mice. [PDF]

open access: yesJ Pharmacol Exp Ther
McClintic WT   +7 more
europepmc   +1 more source

Is lactic acidosis a cause of exercise induced hyperventilation at the respiratory compensation point? [PDF]

open access: bronze, 2004
Tim Meyer   +4 more
openalex   +1 more source

Comparison of Outcome Between Hypothermia Alert Device and Conventional Temperature Recording in Babies Getting Kangaroo Mother Care

open access: yesReproductive, Female and Child Health, Volume 4, Issue 3, September 2025.
ABSTRACT Background Hypothermia is a significant risk factor for newborn morbidity and mortality. Thus, thermoregulation is one of the central components of newborn care. Continuous temperature monitoring can prevent prolonged hypothermia and, subsequently, adverse outcomes.
Azmery Saima   +7 more
wiley   +1 more source

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