Results 171 to 180 of about 104,239 (297)
Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini +7 more
wiley +1 more source
Phenol Neurolysis in Pain and Palliative Medicine
Pain Practice, Volume 26, Issue 5, June 2026.ABSTRACT Background Pain is a common symptom in palliative care and affects patients' quality of life considerably. Standard analgesics are sometimes insufficient and are associated with substantial side effects. Neurolysis, the targeted destruction of nerves using thermal or chemical agents, offers an additional option for managing localized pain in ...
Jeroen H. A. Creemers +6 more
wiley +1 more source
A Study of Death by Crucifixion With Attempted Explanation of the Death of Jesus Christ [PDF]
, 1994 Holoubek, Alice Baker, Holoubek, Joe E.
core +1 more source
FEBS Open Bio, Volume 16, Issue 5, Page 885-905, May 2026.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Genetic Contribution to Asthma Informs Acute Chest Syndrome Pathophysiology and Risk Stratification
American Journal of Hematology, Volume 101, Issue 5, Page 961-971, May 2026.ABSTRACT Acute chest syndrome (ACS) is a severe complication of sickle cell disease (SCD) occurring in ~50% of patients, some presenting frequent episodes. We lack tools to identify patients at high risk of ACS occurrence or frequent episodes. Epidemiological studies have found an association between asthma and ACS, but whether this link is causal is ...
Sara El Aouhel +10 more
wiley +1 more source
Case Report: Antifreeze Ingestion and Urine Fluorescence [PDF]
, 2020 Chin, Meigra Myers, Varshavsky, Taras
core
Severe, Non‐apneic Respiratory Dysfunction and Hypoxia following Generalized Convulsive Seizures
Annals of Neurology, Volume 99, Issue 5, Page 1263-1276, May 2026.Objective Sudden unexpected death in epilepsy (SUDEP) is a devastating consequence of some generalized convulsive seizures (GCS). Recent work has focused on seizure related apnea as a biomarker of SUDEP risk, frequently without characterizing the adequacy of non‐apneic ventilation or identifying other dysfunctional breathing patterns.
Haley E. Pysick +9 more
wiley +1 more source
Trimethoprim/Sulfamethoxazole‐Induced Systemic Toxic Epidermal Necrolysis Syndrome: A Case Report
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT Trimethoprim/sulfamethoxazole can induce life‐threatening toxic epidermal necrolysis. Early recognition, immediate drug cessation, and multidisciplinary supportive care are critical. Even with aggressive therapy, mortality remains high, and SCORTEN score aids in prognostication.
Qing Wang, Litong Chen, Wen Ye
wiley +1 more source
Inhalation of Isopropyl Alcohol Leading to Acute Severe Toxicity: A Case Report
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT This case represents the first reported instance of adult isopropyl alcohol inhalation intoxication with a rapid onset (2 h) and initially negative serum and urine ketones. It highlights that early isopropyl alcohol intoxication may not exhibit the typical clinical features, such as respiratory depression, altered mental status, and positive ...
Ben Thiravetyan +7 more
wiley +1 more source