Results 101 to 110 of about 12,303,189 (383)

Risk factors for Haemophilus influenzae and pneumococcal respiratory tract colonization in CVID [PDF]

open access: yes, 2018
To the Editor: Disease-specific studies focused on infection risk in common variable immune deficiencies (CVIDs) are needed to define strategies for controlling respiratory infections predominantly due to bacteria such as Streptococcus pneumoniae and ...
Camilli, Romina   +10 more
core   +1 more source

Sarcopenia and frailty in chronic respiratory disease

open access: yesChronic Respiratory Disease, 2017
Sarcopenia and frailty are geriatric syndromes characterized by multisystem decline, which are related to and reflected by markers of skeletal muscle dysfunction.
A. Bone, N. Hepgul, S. Kon, M. Maddocks
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Airway basal stem cell-derived extracellular vesicles modulate proliferation, migration and collagen deposition of fibroblasts

open access: yesStem Cell Research & Therapy
Background Human bronchial epithelial cell-derived extracellular vesicles have demonstrated the ability to attenuate fibroblasts activation. However, the specific key effector cell populations mediating this inhibitory effect remain unidentified.
Lisi Luo   +13 more
doaj   +1 more source

Nasal fibrosis: long-term follow up of four cases of eosinophilic angiocentric fibrosis [PDF]

open access: yes, 2005
Eosinophilic angiocentric fibrosis is a rare, benign cause of submucosal thickening and fibrosis within the upper respiratory tract. It predominantly affects the nose although cases have been reported in the subglottis.
Gallimore, A, Lund, VJ, Paun, S
core   +1 more source

Inhaled Therapy in Respiratory Disease: The Complex Interplay of Pulmonary Kinetic Processes

open access: yesCanadian Respiratory Journal, 2018
The inhalation route is frequently used to administer drugs for the management of respiratory diseases such as asthma or chronic obstructive pulmonary disease.
J. M. Borghardt, C. Kloft, Ashish Sharma
semanticscholar   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Rituximab induced sympathetic crashing acute pulmonary oedema in a patient with interstitial lung disease: a rare and lifethreatening complication

open access: yesAsian Journal of Internal Medicine
Rituximab is a monoclonal antibody widely used to treat autoimmune diseases and haematologic malignancies. Although generally well tolerated, it can cause severe infusion-related reactions, including pulmonary complications.
K. Maduranga   +3 more
doaj   +1 more source

A Role for Neutrophils in Viral Respiratory Disease

open access: yesFrontiers in Immunology, 2017
Neutrophils are immune cells that are well known to be present during many types of lung diseases associated with acute respiratory distress syndrome (ARDS) and may contribute to acute lung injury.
Jeremy V. Camp, C. Jonsson
semanticscholar   +1 more source

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