Results 101 to 110 of about 12,340,249 (385)

Antimicrobial use Guidelines for Treatment of Respiratory Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases [PDF]

open access: yes, 2017
Respiratory tract disease can be associated with primary or secondary bacterial infections in dogs and cats and is a common reason for use and potential misuse, improper use, and overuse of antimicrobials.
Allen   +101 more
core   +4 more sources

Inhaled Therapy in Respiratory Disease: The Complex Interplay of Pulmonary Kinetic Processes

open access: yesCanadian Respiratory Journal, 2018
The inhalation route is frequently used to administer drugs for the management of respiratory diseases such as asthma or chronic obstructive pulmonary disease.
J. M. Borghardt, C. Kloft, Ashish Sharma
semanticscholar   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Airway basal stem cell-derived extracellular vesicles modulate proliferation, migration and collagen deposition of fibroblasts

open access: yesStem Cell Research & Therapy
Background Human bronchial epithelial cell-derived extracellular vesicles have demonstrated the ability to attenuate fibroblasts activation. However, the specific key effector cell populations mediating this inhibitory effect remain unidentified.
Lisi Luo   +13 more
doaj   +1 more source

The air we breathe [PDF]

open access: yes, 1993
Air pollution has been associated with respiratory ill health for centuries and in recent years much research effort has gone into quantifying the risks and elucidating the mechanisms. Respiratory disease, mostly of the airways is second only by a narrow
Ebejer, Martin J.
core  

Identifying Clusters in Bayesian Disease Mapping [PDF]

open access: yes, 2013
Disease mapping is the field of spatial epidemiology interested in estimating the spatial pattern in disease risk across $n$ areal units. One aim is to identify units exhibiting elevated disease risks, so that public health interventions can be made ...
Anderson, Craig, Dean, Nema, Lee, Duncan
core   +1 more source

A Role for Neutrophils in Viral Respiratory Disease

open access: yesFrontiers in Immunology, 2017
Neutrophils are immune cells that are well known to be present during many types of lung diseases associated with acute respiratory distress syndrome (ARDS) and may contribute to acute lung injury.
Jeremy V. Camp, C. Jonsson
semanticscholar   +1 more source

Epidemiology, virology, and clinical features of severe acute respiratory syndrome -coronavirus-2 (SARS-CoV-2; Coronavirus Disease-19)

open access: yesClinical and experimental pediatrics, 2020
A cluster of severe pneumonia of unknown etiology in Wuhan City, Hubei province in China emerged in December 2019. A novel coronavirus named severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was isolated from lower respiratory tract sample as ...
Su Eun Park
semanticscholar   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Correction to: Efficacy and safety of tetramethylpyrazine phosphate on pulmonary hypertension: study protocol for a randomized controlled study

open access: yesTrials, 2020
After publication of our article [1] the authors have notified us of two typos in the Trial status.
Yuqin Chen   +8 more
doaj   +1 more source

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