Respiratory muscles dysfunction and respiratory diseases [PDF]
This review presents an analysis of the literature on the topic of respiratory muscle (RM) dysfunction in various forms of respiratory pathology: chronic obstructive pulmonary disease (COPD), asthma, community-acquired pneumonia, idiopathic pulmonary fibrosis (IPF), sarcoidosis and interstitial lung diseases (ILD), associated with systemic connective ...
B I Geltser +3 more
openaire +3 more sources
Background Sputum biopsies offer unique advantages such as non-invasiveness and convenient collection. The one investigation so far on sputum for genome profiling in advanced non-small cell lung cancer (aNSCLC) suggested promising performance.
Xiaohong Xie +14 more
doaj +1 more source
Combined exome and whole-genome sequencing identifies mutations in ARMC4 as a cause of primary ciliary dyskinesia with defects in the outer dynein arm [PDF]
Primary ciliary dyskinesia (PCD) is a rare, genetically heterogeneous ciliopathy disorder affecting cilia and sperm motility. A range of ultrastructural defects of the axoneme underlie the disease, which is characterised by chronic respiratory symptoms ...
Alexandros Onoufriadis +45 more
core +3 more sources
Incidence of viral respiratory infections in a prospective cohort of outpatient and hospitalized children aged ≤5 years and its associated cost in Buenos Aires, Argentina [PDF]
Background: Although information about the incidence of viral respiratory illnesses and their associated cost can help health officials explore the value of interventions, data are limited from middle-income countries.
Azziz Baumgartner, Eduardo +6 more
core +1 more source
MUC5B regulates goblet cell differentiation and reduces inflammation in a murine COPD model
Background Airway mucus hypersecretion is one of the important pathological features of chronic obstructive pulmonary disease (COPD). MUC5B is the main mucin expressed in the airways of COPD patients and has been indicated to play an important role in ...
Xuan Huang +5 more
doaj +1 more source
Severe acute respiratory syndrome (SARS): breathtaking progress [PDF]
Reports of a new severe respiratory disease, now defined as severe acute respiratory syndrome (SARS), began to emerge from Guangdong, in southern China, in late 2002.
Bhagani, S, Gillespie, SH, Hawkey, PM
core +2 more sources
Clinical utility of cardiac troponin measurement in COVID-19 infection [PDF]
The novel coronavirus SARS-CoV-2 causes the disease COVID-19, a severe acute respiratory syndrome. COVID-19 is now a global pandemic and public health emergency due to rapid human-to-human transmission.
Gaze, D.C., Gaze, D.C.
core +1 more source
Background The burden of asthma in terms of premature death or reduced quality of life remains a huge issue. It is of great importance to evaluate asthma burden geographically and time trends from 1990 to 2019 and to assess the contributions of age ...
Zhufeng Wang +7 more
doaj +1 more source
Model evaluation of target product profiles of an infant vaccine against respiratory syncytial virus (RSV) in a developed country setting [PDF]
Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract disease in children worldwide and is a significant cause of hospital admissions in young children in England.
Kinyanjui, Timothy +5 more
core +1 more source
Estimation of lung age via a spline method and its application in chronic respiratory diseases
Lung age is a simplified concept that makes spirometry data easier to understand, but it is not widely used due to limitations in estimation methods. The aim of this study was to develop new equations to estimate lung age and to explore the application ...
Xiaolin Liang +7 more
doaj +1 more source

