Results 71 to 80 of about 486,544 (375)

Respiratory distress in small for gestational age infants based on local newborn curve prior to hospital discharge

Frontiers in Pediatrics, 2022
BackgroundRespiratory distress in newborns, which may lead to risks of morbidity and death, is one of the reasons for a referral to the more advanced health facilities.
Ekawaty Lutfia Haksari, Mohammad Hakimi, Djauhar Ismail   +2 more
doaj   +1 more source

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source

Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries [PDF]

, 2016
IMPORTANCE: Limited information exists about the epidemiology, recognition, management, and outcomes of patients with the acute respiratory distress syndrome (ARDS).
Alejandro, Risso V., Alvarez, Javier, Bellani, Giacomo, Bettini, Lisandro R., Bisso, Mariano Carboni, Brochard, Laurent, Cani, Alma, Cardonnet, Luis P., Chena, Ariel, Conti, Sara, Daldin, Julio, Dellera, Christian, Esteban, Andres, Estenssoro, Elisa, Fan, Eddy, Fernandez, Ruben O., Francois, Guy M., Gattinoni, Luciano, Grubissich, Nicolas, Ilutovich, Santiago, Insaurralde, Carolina S., Laffey, John G., Larsson, Anders, Lovazzano, Pablo, Madotto, Fabiana, McAuley, Daniel F., Nunci, Lordian, Osman, Emilio M., Pellegrini, Carlos A., Pesenti, Antonio, Pham, Tài, Plotnikow, Gustavo A., Pozo, Norberto C., Rabboni, Francesca, Ranieri, Marco, Rubenfeld, Gordon, Saenz, María G., Schultz, Marcus J., Setten, Mariano G., Simonis, Fabienne D., Slutsky, Arthur S., Sula, Hektor, Thompson, B. Taylor, Tiribelli, Norberto, van Haren, Frank, Vasquez, Daniela N., Villar, Veronica, Vinzio, Mauricio, Wrigge, Hermann, Zazu, Alan   +49 more
core   +3 more sources

Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury

Advanced Science, EarlyView.
Dipyridamole acts as a clinically used compound to suppress ferroptosis. Dipyridamole down‐regulates the expression of RNF126, which is an E3 ligase to ubiquitinate SLC7A11 for proteasome degradation. The deficiency of SLC7A11 largely abolishes the protective role of dipyridamole both in vitro and in vivo.
Xiao Zhuang, Shuang Shi, Shuo Liu, Yaqiong Jiao, Bin Huang, Yinghong Yang, Li Yang, Xinquan Yang, Hui Wang, Chunhui Liang, Dandan Song, Huaxiang Yu, Dan Zou, Qi Sun, Shu Yang, Chengqian Yin, Jian Li, Yiming Liu, Junxia Min, Fudi Wang, Yong Nian, Lutao Du, Bo Chu   +22 more
wiley   +1 more source

A Touch Enabled Hemodynamic and Metabolic Monitor

Advanced Science, EarlyView.
This work presents a touch‐based hybrid platform for simultaneous monitoring of vital signs and sweat metabolites. With a simple tri‐finger touch of 4–6 min, users can concurrently get to know their glucose, uric acid, cortisol levels from fingertip sweat, along with blood pressure and heart rate.
Omeed Djassemi, Tamoghna Saha, Ponnusamy Nandhakumar, Muhammad Inam Khan, Hannah Fishman, Sara Earney, Chochanon Moonla, Yuchen Xu, Henry Thai, Sofia Morales‐Fermin, Gyeongho Kim, Rhea Park, Beya Acot, Oscar Wu, Cannon Wurster, An‐Yi Chang, Christopher Cheung, Julia Silberman, Shichao Ding, Joseph Wang   +19 more
wiley   +1 more source

Novel translational approaches to the search for precision therapies for acute respiratory distress syndrome. [PDF]

, 2017
In the 50 years since acute respiratory distress syndrome (ARDS) was first described, substantial progress has been made in identifying the risk factors for and the pathogenic contributors to the syndrome and in characterising the protein expression ...
Calfee, Carolyn S, Meyer, Nuala J
core   +1 more source

Mechanical Stress Induced NOX2 Promotes Endothelial Dysfunction in Ventilator‐Induced Lung Injury: Potential Treatment with Quercetin

Advanced Science, EarlyView.
Abnormal mechanical stretch induced by mechanical ventilation (MV) disrupts endothelial junctions via the NOX2/ROS/CaMKII/ERK1/2 axis both in human aortic endothelial cells (HAECs) in vitro and in ventilator‐induced lung injury (VILI) in mice. Quercetin, an antioxidant predicted to bind to NOX2, can effectively prevent mechanical stretch‐induced ...
Tao Jiang, Yabing Zhang, Zhiye Guo, He Ren, Weiyi Hu, Qingping Yao, Yunlong Huo, Yingxin Qi, Kai Huang   +8 more
wiley   +1 more source

A hybrid machine learning/deep learning COVID-19 severity predictive model from CT images and clinical data [PDF]

arXiv, 2021
COVID-19 clinical presentation and prognosis are highly variable, ranging from asymptomatic and paucisymptomatic cases to acute respiratory distress syndrome and multi-organ involvement. We developed a hybrid machine learning/deep learning model to classify patients in two outcome categories, non-ICU and ICU (intensive care admission or death), using ...
arxiv  

Effectiveness of blood transfusions and risk factors for mortality in children aged from 1 month to 4 years at the Bon Marche Hospital, Bunia, Democratic Republic of Congo [PDF]

, 2012
Objective  To assess the effectiveness of blood transfusions in a hospital of north-eastern Democratic Republic of the Congo. Methods  Prospective study of children admitted for severe anaemia.
Akech, Calis, Dalmas, Evans, Hassall, Madjdpour, Marcucci, Molyneux, Pedro, Phiri   +9 more
core   +2 more sources

Precision‐Guided Stealth Missiles in Biomedicine: Biological Carrier‐Mediated Nanomedicine Hitchhiking Strategy

Advanced Science, EarlyView.
Diagram illustrating the binding methods of NPs and biological barriers. The biological carrier‐mediated nanomedicine hitchhiking strategy (BCM‐NHS) utilizes two distinct techniques: the surface‐based “Backpack” method, which relies on ligand‐receptor binding, covalent conjugation, and non‐covalent binding, and the encapsulated “Trojan horse” approach,
Yuyan Zhou, Xinyue Wang, Deyu Zhang, Hanxiao Cui, Xiaorong Tian, Wei Du, Zhenghui Yang, Dongling Wan, Zhiwei Qiu, Chao Liu, Zhicheng Yang, Lizhihong Zhang, Qiusheng Yang, Xuefeng Xu, Wenhao Li, Dong Wang, Haojie Huang, Wencheng Wu   +17 more
wiley   +1 more source