Results 201 to 210 of about 1,060,038 (295)

Skullcapflavone II Inhibits SLC1A4‐Mediated L‐Serine Uptake and Promotes Mitochondrial Damage in Gastric Cancer

Advanced Science, EarlyView.
Skullcapflavone II (SkII) significantly alters serine metabolism in gastric cancer cells by directly targeting the L‐serine transporter SLC1A4, thereby inhibiting L‐serine uptake rather than de novo synthesis. This disruption of serine metabolism by SkII leads to increased oxidative stress and consequent mitochondrial damage.
Jing Zhao, Yu‐Bo Ma, Rui‐Hong Xia, Zheng‐Chen Jiang, Ying Zhou, Ya‐Nan Wang, Meng‐Yan Yang, Jing‐Jie Dai, Tao Zhu, Li‐Bin Pan, Li Yuan   +10 more
wiley   +1 more source

Confronting Hypoxemic Respiratory Failure in Africa: If Not Now, When? [PDF]

Ann Am Thorac Soc
Cummings MJ, Bakamutumaho B.
europepmc   +1 more source

P42 Factors affecting the duration of acute non invasive ventilation required in patients with acute hypercapnic respiratory failure [PDF]

, 2015
Abigail Bishopp, Nadia Sayeed, Amy Oakes, Ben Beauchamp, B. N. Chakraborty, Rahul Mukherjee   +5 more
openalex   +1 more source

Type II Alveolar Epithelial Cells Promote Sepsis‐Induced Immunosuppression in Alveolar Macrophages via Exosomal lncRNA Rmrp Release

Advanced Science, EarlyView.
The S100A4/STAT3 axis promotes Rmrp transcription in AEC‐IIs and Rmrp expression in AEC‐II‐derived exosomes. Upon entry into AMs, Rmrp binds to and blocks the ubiquitination and degradation of ZFP36. Increased ZFP36 induced Pfkfb3 mRNA decay by binding to AREs in the 3′ UTR, curbing glycolysis and immune responses of AMs and aggravating SII and ...
Chengxi Liu, Weixia Xuan, Song Cao, Huayun Jia, Qian Wu, Xiaowu Tan, Qijie Wang, Xiaojun Li, Lisha Ding, Yaru Xiong, Meiyun Zhao, Longcheng Zheng, Yunzhu Xi, Jianhua Tan, Rong Li, Xulong Zhang, Wenjie Liu, Xu Wu   +17 more
wiley   +1 more source

Heterotopic Nasopharyngeal Glioneuroma as a Cause of Respiratory Failure in a Newborn. [PDF]

Cureus
Sohmer JS, Mohiuddin M, Ostrower ST.
europepmc   +1 more source

Usefulness of Respiratory Stability Time-Guided Management to Prevent Readmission of Chronic Heart Failure Patients at Home: A Multicenter, Single-Arm, Open-Label Clinical Study (ITMETHOD-HF-III) [PDF]

Teruhiko Imamura, Yasuhiro Akazawa, Shunsuke Saito, Yasushi Sakata, Shigeru Miyagawa, Tomomi Yamada, Hidetsugu Asanoi, Koichiro Kinugawa   +7 more
openalex   +1 more source

Hepatitis E Virus ORF1 Polyprotein Harbors a Pocket‐Like Cavity That Is Vital for Virus Replication and Represents a Novel Antiviral Target

Advanced Science, EarlyView.
Within the hepatitis E virus (HEV) ORF1 polyprotein, the X domain interacts with viral RNA‐dependent RNA polymerase (RdRp), forming a functional “pocket‐like” cavity (PC) that is crucial for viral replication. Structure‐based screening, surface plasmon resonance (SPR) assays, and HEV model validation collectively identify saikosaponin D and ...
Xiaohui Ding, Dou Zeng, Dan Liu, Yingying Bian, Bin Li, Zheng Li, Qiudi Li, Shiquan Liang, Yunlong Si, Qili Yao, Yibo Ding, Jiahui Zhu, Xiangyang Li, Kuiyang Zheng, Hongbo Guo, Wenshi Wang   +15 more
wiley   +1 more source

COVID-19-Related Croup With Acute Respiratory Failure. [PDF]

Kaohsiung J Med Sci
Hsu CK, Hsieh TH, Liu YC, Chen IC.
europepmc   +1 more source

Postmortem changes in lungs in severe closed traumatic brain injury complicated by acute respiratory failure

, 2013
V. A. Tumanskiy, S. I. Tertnishniy
openalex   +2 more sources

Non-invasive ventilation indication for critically ill cancer patients admitted to the intensive care unit for acute respiratory failure (ARF) with associated cardiac dysfunction: Results from an observational study

, 2020
Colombe Saillard, Damien Mallet, Laurent Chow‐Chine, Magali Bisbal, Marion Faucher, Antoine Sannini, Djamel Mokart   +6 more
openalex   +2 more sources