Results 21 to 30 of about 1,060,038 (295)

Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure [PDF]

, 2019
Heart failure is a leading cause of mortality, yet our understanding of the genetic interactions underlying this disease remains incomplete. Here, we harvest 1352 healthy and failing human hearts directly from transplant center operating rooms, and ...
Ashley, Euan A., Bernstein, Daniel, Brandimarto, Jeff, Cappola, Thomas, Chang, Alex C., Chin, Elizabeth T., Connolly, Andrew, Cordero, Pablo, Depaoli-Roach, Anna A., Dewey, Frederick, Erbilgin, Ayca, Glazer, Nicole, Gloudemans, Michael J., Hakonarson, Hakon, Hannenhalli, Sridhar, Huang, Yong, Li, Hongzhe, Li, Mingyao, Lusis, Aldons J., Malloy, Christine, Margulies, Kenneth B., Montgomery, Stephen B., Moravec, Christine S., Morley, Michael, Parikh, Victoria N., Pavlovic, Aleksandra, Ritter, Scott, Shang, Ching, Skreen, Jamie, Smith, Kevin S., Tang, W. H. Wilson, Waggott, Daryl, Wheeler, Matthew T., Zaleta, Kathia, Zhao, Mingming   +34 more
core   +2 more sources

Restricted spirometry and cardiometabolic comorbidities: results from the international population based BOLD study

Respiratory Research, 2022
Background Whether restricted spirometry, i.e. low Forced Vital Capacity (FVC), predicts chronic cardiometabolic disease is not definitely known. In this international population-based study, we assessed the relationship between restricted spirometry and
Katarzyna Kulbacka-Ortiz, Filip J. J. Triest, Frits M. E. Franssen, Emiel F. M. Wouters, Michael Studnicka, William M. Vollmer, Bernd Lamprecht, Peter G. J. Burney, Andre F. S. Amaral, Lowie E. G. W. Vanfleteren   +9 more
doaj   +1 more source

Case report: Coronary allograft vasculopathy: an accurate reflection of the histopathological findings on cardiovascular magnetic resonance imaging

Frontiers in Cardiovascular Medicine, 2023
Heart transplant recipients undergo extensive invasive and non-invasive postoperative screening to exclude complications, such as allograft rejection and vasculopathy. Cardiac magnetic resonance imaging is a non-invasive, non-irradiating, diagnostic tool
Carmela Napolitano, Giorgia Grutter, Paola Francalanci, Antonio Amodeo, Aurelio Secinaro   +4 more
doaj   +1 more source

CESAR: conventional ventilatory support vs extracorporeal membrane oxygenation for severe adult respiratory failure. [PDF]

, 2006
BACKGROUND: An estimated 350 adults develop severe, but potentially reversible respiratory failure in the UK annually. Current management uses intermittent positive pressure ventilation, but barotrauma, volutrauma and oxygen toxicity can prevent lung ...
Clemens, Felicity, Elbourne, Diana, Firmin, Richard, Hardy, Pollyanna, Hibbert, Clare, Killer, Hilliary, Mugford, Miranda, Peek, Giles J, Thalanany, Mariamma, Tiruvoipati, Ravin, Truesdale, Ann, Wilson, Andrew   +11 more
core   +3 more sources

Similarity measurements of B cell receptor repertoire in baseline mice showed spectrum convergence of IgM

BMC Immunology, 2022
Background The B cell receptor (BCR) repertoire is highly diverse among individuals. Poor similarity of the spectrum among inbred baseline mice may limit the ability to discriminate true signals from those involving specific experimental factors.
Hongkai Wu, Zhichao Zhou, Shi Xie, Rong Yan, Mingxing Gong, Xingui Tian, Zhanhui Wang   +6 more
doaj   +1 more source

Automated Home Oxygen Delivery for Patients with COPD and Respiratory Failure: A New Approach [PDF]

, 2020
Long-term oxygen therapy (LTOT) has become standard care for the treatment of patients with chronic obstructive pulmonary disease (COPD) and other severe hypoxemic lung diseases.
Lara Doña, Alejandro, León Jiménez, Antonio, Muñoz Zara, Pilar, Sánchez Morillo, Daniel   +3 more
core   +1 more source

Differences in cerebral oxygenation during exercise in patients with idiopathic pulmonary fibrosis with and without exertional hypoxemia: does exercise intensity matter?

Pulmonology, 2023
Introduction and Objectives Patients with idiopathic pulmonary fibrosis (IPF) present respiratory derangements at rest and during exercise, accompanied by exercise intolerance.
K. Dipla, A.K. Boutou, A. Markopoulou, S. Papadopoulos, S. Kritikou, G. Pitsiou, I. Stanopoulos, I. Kioumis, A. Zafeiridis   +8 more
doaj   +1 more source

Early high flow nasal cannula therapy in bronchiolitis, a prospective randomised control trial (protocol): A Paediatric Acute Respiratory Intervention Study (PARIS) [PDF]

, 2015
Background Bronchiolitis imposes the largest health care burden on non-elective paediatric hospital admissions worldwide, with up to 15 % of cases requiring admission to intensive care.
Andreas Schibler, Donna Franklin, Ed Oakley, Franz E. Babl, Jennifer A. Whitty, Jeremy S. Furyk, Jocelyn Neutze, John Fraser, Kam Sinn, Kristen Gibbons, Luregn J. Schlapbach, null null, Simon S. Craig, Stuart Dalziel   +13 more
core   +3 more sources

Variation in information needs of patients with interstitial lung disease and their family caregivers according to long-term oxygen therapy: a descriptive study

BMC Pulmonary Medicine, 2023
Background The information needs of patients and their families regarding interstitial lung disease (ILD) have yet to be studied in detail, and few reports have examined the differences in information needs according to patient status.
Ryuhei Sato, Tomohiro Handa, Kiminobu Tanizawa, Toyohiro Hirai   +3 more
doaj   +1 more source

Airway bacterial and fungal microbiome in chronic obstructive pulmonary disease

Medicine in Microecology, 2021
Little is known about airway mycobiome, and its relationship with bacterial microbiome in chronic obstructive pulmonary disease (COPD). Here we report the first simultaneous characterization of sputum bacterial and fungal microbiome in 84 stable COPD and
Haiyue Liu, Zhenyu Liang, Nannan Cao, Xinzhu Yi, Xilan Tan, Zuheng Liu, Fengyan Wang, Yuqiong Yang, Chunxi Li, Zhiming Xiang, Yan He, Jin Su, Zhang Wang, Rongchang Chen, Hongwei Zhou   +14 more
doaj   +1 more source