Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in acute lung injury to reduce pulmonary dysfunction (HARP-2) trial : study protocol for a randomized controlled trial [PDF]
, 2012 Acute lung injury (ALI) is a common devastating clinical syndrome characterized by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure.
A Mercat +31 more
core +1 more source
Physiopathological rationale of using high-flow nasal therapy in the acute and chronic setting: A narrative review [PDF]
, 2019 Chronic lung disease and admissions due to acute respiratory failure (ARF) are becoming increasingly common. Consequently, there is a growing focus on optimizing respiratory support, particularly non-invasive respiratory support, to manage these ...
Cortegiani A. +2 more
core +1 more source
Monaldi Archives for Chest Disease, 2015 This report describes a case of a 73-year-old man with chronic obstructive pulmonary disease (COPD) grade D. His walking abilities were seriously compromised due to chronic respiratory failure and arthrosis causing chronic joint pain.
Daniela Parola +2 more
doaj +1 more source
Evaluation of Functional Condition of Respiratory Muscles of Patients with a Complicated Bronchial Asthma Pathology and Chronic Obstructive Pulmonary Diseases [PDF]
, 2017 The aim of the research was to study the functional state of respiratory muscles and neuro-respiratory drive in patients with a combined pathology of bronchial asthma and chronic obstructive pulmonary disease.The functional condition of the respiratory ...
Feschenko, Y. (Yuriy) +1 more
core +2 more sources
Sarcoidosis Presenting as Acute Respiratory Distress Syndrome. [PDF]
, 2018 Sarcoidosis is a multisystem granulomatous disease of unknown origin. It typically involves the lungs and mediastinal lymph nodes in a chronic fashion. However, acute syndrome has been reported possibly in response to systemic release of proinflammatory ...
Chan, Vincent +3 more
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Frequency and functional translation of low muscle mass in overweight and obese patients with COPD
Respiratory Research, 2021 Background Cut offs for fat-free mass index (FFMI) and appendicular skeletal muscle mass index (ASMI) are available for diagnosing low muscle mass in patients with COPD. This study aimed to investigate: (1) the frequency of low muscle mass (FFMI and ASMI)
Felipe V. C. Machado +9 more
doaj +1 more source
Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure [PDF]
, 2019 Heart failure is a leading cause of mortality, yet our understanding of the genetic interactions underlying this disease remains incomplete. Here, we harvest 1352 healthy and failing human hearts directly from transplant center operating rooms, and ...
Ashley, Euan A. +34 more
core +2 more sources
Long Term Non-invasive Ventilation in Children With Central Hypoventilation
Frontiers in Pediatrics, 2020 Central hypoventilation (CH) is a quite rare disorder caused by some congenital or acquired conditions. It is featured by increased arterial concentration of serum carbon dioxide related to an impairment of respiratory drive. Patients affected by CH need
Maria Giovanna Paglietti +5 more
doaj +1 more source
Respiratory Research, 2022 Background Whether restricted spirometry, i.e. low Forced Vital Capacity (FVC), predicts chronic cardiometabolic disease is not definitely known. In this international population-based study, we assessed the relationship between restricted spirometry and
Katarzyna Kulbacka-Ortiz +9 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2023 Heart transplant recipients undergo extensive invasive and non-invasive postoperative screening to exclude complications, such as allograft rejection and vasculopathy. Cardiac magnetic resonance imaging is a non-invasive, non-irradiating, diagnostic tool
Carmela Napolitano +4 more
doaj +1 more source