Results 61 to 70 of about 4,787,434 (307)

Evaluating four –variable screening tool in european population of a sleep clinic for assessing obstructive sleep apnea syndrome

open access: yesAsian Journal of Medical Sciences, 2015
Background: Different questionnaires have been used to evaluate patients with Obstructive sleep apnea/hypopnea syndrome (OSAHS). The 4-Variable screening tool (4-V) was developed and validated in Asian population for identifying moderate to severe OSAHS.
Athanasia Pataka
doaj   +1 more source

Association between muscle quality index and pulmonary function in post-COVID-19 subjects

open access: yesBMC Pulmonary Medicine, 2023
Background The SARS-CoV2 pandemic impacted many critically ill patients, causing sequelae, affecting lung function, and involving the musculoskeletal system. We evaluated the association between lung function and muscle quality index in severely ill post-
Dulce González-Islas   +9 more
doaj   +1 more source

The Role of high flow nasal therapy in Intensive Care Units

open access: yesJournal of Education, Health and Sport, 2023
Introduction and purpose: High Flow Nasal Therapy is quite new respiratory support method, although recently it became more popular – especially during COVID-19 pandemic.
Michał Wyszkowski   +8 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Time-varying intensity of mechanical ventilation and mortality in patients with acute respiratory failure: a registry-based, prospective cohort study

open access: yesThe Lancet Respiratory Medicine, 2020
Background Mortality in acute respiratory failure remains high despite the use of lung-protective ventilation. Recent studies have shown an association between baseline ventilation parameters (driving pressure or mechanical power) and outcomes for ...
M. Urner   +5 more
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Prone Positioning in Awake, Nonintubated Patients With COVID-19 Hypoxemic Respiratory Failure

open access: yesJAMA Internal Medicine, 2020
This cohort study investigates whether the prone position is associated with improved oxygenation and decreased risk for intubation in spontaneously breathing patients with severe COVID-19 hypoxemic respiratory failure.
Alison E. Thompson   +3 more
semanticscholar   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Respiratory physiology of COVID-19-induced respiratory failure compared to ARDS of other etiologies

open access: yesCritical Care, 2020
Background Whether respiratory physiology of COVID-19-induced respiratory failure is different from acute respiratory distress syndrome (ARDS) of other etiologies is unclear.
D. Grieco   +19 more
semanticscholar   +1 more source

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