Results 41 to 50 of about 2,363,330 (306)

Characterising COVID-19 school and childcare outbreaks in Canada in 2021: a surveillance study

BMJ Public Health
Background In January 2021, the Public Health Agency of Canada launched the Canadian COVID-19 Outbreak Surveillance System to monitor outbreaks by setting. Schools and childcare centres were identified as settings of interest, as children play a key role
Kaitlin Patterson, Erin McGill, Demy Dam, Anna Bellos, Cameron Mark Coulby, Rachel McCormick   +5 more
doaj   +1 more source

What influences antibiotic sales in rural Bangladesh? A drug dispensers’ perspective

Journal of Pharmaceutical Policy and Practice, 2020
Background Antibiotic resistance poses a great threat to global health, especially in low- and middle-income countries with a high infectious disease burden and limited resources.
Mohammad Abdul Matin, Wasif Ali Khan, Mohammad Mahbubul Karim, Sabeena Ahmed, Johannes John-Langba, Osman A. Sankoh, Margaret Gyapong, John Kinsman, Heiman Wertheim   +8 more
doaj   +1 more source

A Rare Case of Staphylococcal Toxic Shock Syndrome in a Neonate

Case Reports in Infectious Diseases, 2022
Staphylococcus toxic shock syndrome (TSS) is not well described in neonates. The present criteria for diagnosis of TSS have not yet been validated in neonates.
Nipun Shrestha, Alisha Joshi, Yumiko Hayashi, Dhruba Shrestha, Bhim Gopal Dhoubhadel   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Persistent systemic interleukin-6 elevation after community-acquired pneumonia is associated with one-year mortality

Respiratory Research
Community-acquired pneumonia (CAP) remains a leading global cause of mortality and the foremost infectious cause of death. Emerging evidence suggests that its impact extends beyond the acute phase.
Mónica Piqueras, Paula González-Jiménez, Ana Latorre, Noé Mengot, Jordi Tortosa-Carreres, Álvaro Gimeno, Belén Picazos, Miguel Porcar, Rosario Menéndez, Raúl Méndez   +9 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Respiratory health and endotoxin: associations and modification by CD14/-260 genotype [PDF]

, 2011
Exposure to endotoxin has been associated with increased respiratory symptoms and decrements in lung function in occupational settings but little is known about the health effects of domestic exposure in adults.
Jarvis, D., Heederik, D., Svanes, C., M. Kogevinas, Dep IRAS, Norbäck D, D. Jarvis, J. P. Zock, Olivieri, Mario, Bakolis, I., Jarvis, D, C. M. Chen, on behalf of the Indoor group of the ECRHS, S. Guerra, D. Norback, G. Verlato, Norback, D., Bakolis I, Ramasamy, A, Svanes C, Jarvis D, Ramasamy A, Chen CM, J. Heinrich, Guerra, S., Chen, C.M., Chen, C. M., ?, ?, Castro-Giner, F., D. Heederik, null null, Kogevinas, M, Zock JP, Doekes, G., A. Nevalainen, VERLATO, Giuseppe, Nevalainen, A., HITEA Study Group (), Nevalainen, A, Chen, CM, Olivieri, M., Norbäck, D, Guerra, S, Svanes, C, Indoor Group of the ECRHS, I. Bakolis, Castro-Giner, F, Norbäck, Dan,, Kogevinas, M., Verlato, G., Heinrich, J, Risk Assessment of Toxic and Immunomodulatory Agents, Zock, JP, Bakolis, I, Olivieri, M, the Work Package 10 group of HITEA, Heinrich, J., Guerra S, Zock, J. P., Zock, J P, C. Svanes, Heinrich J, Kogevinas M, Chen, C M, Bakolis, I; id_orcid, A. Ramasamy, Verlato, G, Work Package 10 Group of HITEA, Nevalainen A, Doekes, G, Zock, J.P., G. Doekes, Doekes G, M. Olivieri, Heederick D, Ramasamy, A., Heederik, D, F. Castro-Giner   +77 more
core   +1 more source

Respiratory virus infections

Paediatric Respiratory Reviews, 2007
The respiratory tract is a frequent site of infection with a wide range of viruses. Each family of viruses can cause differing clinical syndromes depending on the age of the patient and the immune response. As a corollary, different clinical syndromes can be caused by different families of viruses.
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Antimicrobial approaches against bacterial pathogens which cause lower respiratory system infections

, 2016
Usually, the health-care challenge in the respiratory infections is due to bacterial infections and their resistance to antimicrobials. These kinds of infections evolve rapidly, and for this reason inappropriate doses (for the broad-spectrum coverage ...
L.C.L. Novaes, V. de Carvalho Santos-Ebinuma, Grotto, D., de Carvalho Santos-Ebinuma, V. [UNESP], Gerenutti, M., F.S. Del Fiol, Novaes, L. C.L., M. Gerenutti, Jozala, A. F., D. Grotto, Del Fiol, F. S., A.F. Jozala   +11 more
core   +1 more source