Results 51 to 60 of about 1,287,362 (306)

Characterising COVID-19 school and childcare outbreaks in Canada in 2021: a surveillance study

BMJ Public Health
Background In January 2021, the Public Health Agency of Canada launched the Canadian COVID-19 Outbreak Surveillance System to monitor outbreaks by setting. Schools and childcare centres were identified as settings of interest, as children play a key role
Kaitlin Patterson, Erin McGill, Demy Dam, Anna Bellos, Cameron Mark Coulby, Rachel McCormick   +5 more
doaj   +1 more source

Management of acute bronchitis in healthy adults. [PDF]

, 2004
Acute respiratory infections (ARIs) are the most common infections in humans, accounting for half of all acute conditions each year in the United States. Acute bronchitis episodes represent a significant portion of these illnesses.
Aagaard, Eva, Gonzales, Ralph
core  

Interventions for enhancing adherence to treatment in adults with bronchiectasis [PDF]

, 2015
BackgroundBronchiectasis is characterised by a widening of the airways, leading to excess mucus production and recurrent infection. It is more prevalent in women and those in middle age.
Bradley, Judy M., Elborn, Stuart, Hughes, Carmel, McCullough, Amanda, O'Neill, Brenda, Ryan, Cristin, Thomas, Elizabeth T.   +6 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

High Expression of IL-36γ in Influenza Patients Regulates Interferon Signaling Pathway and Causes Programmed Cell Death During Influenza Virus Infection

Frontiers in Immunology, 2020
As a severe complication of influenza infection, acute respiratory distress syndrome (ARDS) has higher morbidity and mortality. Although IL-36γ has been proven to promote inflammation at epithelial sites and protect against specific pathogen infection ...
Shuai Liu, Shuai Liu, Hui Li, Hui Li, Hui Li, Yeming Wang, Yeming Wang, Yeming Wang, Haibo Li, Haibo Li, Haibo Li, Sisi Du, Sisi Du, Sisi Du, Xiaohui Zou, Xiaohui Zou, Xiaohui Zou, Xulong Zhang, Bin Cao, Bin Cao, Bin Cao, Bin Cao   +21 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Achieving optimal technology and behavioral uptake of single and combined interventions of water, sanitation hygiene and nutrition, in an efficacy trial (WASH benefits) in rural Bangladesh

Trials, 2018
Background Uptake matters for evaluating the health impact of water, sanitation and hygiene (WASH) interventions. Many large-scale WASH interventions have been plagued by low uptake.
Sarker Masud Parvez, Rashidul Azad, Mahbubur Rahman, Leanne Unicomb, Pavani K. Ram, Abu Mohd Naser, Christine P. Stewart, Kaniz Jannat, Musarrat Jabeen Rahman, Elli Leontsini, Peter J. Winch, Stephen P. Luby   +11 more
doaj   +1 more source

Synergistic Activity of Colistin Combined With Auranofin Against Colistin-Resistant Gram-Negative Bacteria

Frontiers in Microbiology, 2021
Colistin-resistant (Col-R) bacteria are steadily increasing, and are extremely difficult to treat. New drugs or therapies are urgently needed to treat infections caused by these pathogens.
Xiaoxuan Feng, Xiaoxuan Feng, Shuai Liu, Shuai Liu, Yang Wang, Yang Wang, Yulin Zhang, Yulin Zhang, Yulin Zhang, Lingxiao Sun, Lingxiao Sun, Haibo Li, Haibo Li, Haibo Li, Chunlei Wang, Chunlei Wang, Chunlei Wang, Yingmei Liu, Yingmei Liu, Yingmei Liu, Bin Cao, Bin Cao, Bin Cao, Bin Cao, Bin Cao   +24 more
doaj   +1 more source

Noninvasive mechanical ventilation in high-risk pulmonary infections: a clinical review [PDF]

, 2014
The aim of this article was to review the role of noninvasive ventilation (NIV) in acute pulmonary infectious diseases, such as severe acute respiratory syndrome (SARS), H1N1 and tuberculosis, and to assess the risk of disease transmission with the use ...
Ambrosino, Nicolino, Depuydt, Pieter, Esquinas, Antonio M, Gay, Peter, Girault, Christophe, Han, Fang, Hui, David S, International NIV Network, on behalf of the, Papadakos, Peter J, Pravinkumar, S Egbert, Scala, Raffaele, Soroksky, Arie   +11 more
core   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source