Results 61 to 70 of about 952,092 (306)

Age-dependent differences in the pathogenesis of bovine respiratory syncytial virus infections related to the development of natural immunocompetence

, 2010
The severity of respiratory syncytial virus (RSV) infections appears to differ with age in both humans and bovines. A primary RSV infection in naïve infants and in young calves runs a more severe course when they are 1–6 months old than in their first ...
Most, R.G., van der, Stockhofe-Zurwieden, N., Schrijver, R.S., Antonis, A.F.G., Poel, W.H.M., van der, Jong, M.C., de, Kimman, T.G.   +6 more
core   +1 more source

Hesitancy towards COVID-19 booster vaccine among healthcare workers in Bangladesh

BMC Health Services Research
Background Despite completing the COVID-19 vaccination series, healthcare workers (HCWs) remain at an elevated risk of re-infection. Booster uptake, though essential for this group, remains poorly characterized among Bangladeshi HCWs.
Homayra Rahman Shoshi, Ahamed Khairul Basher, Ashrak Shad Pyash, Md. Kamal Hossain, Fahmida Chowdhury, Md Zakiul Hassan   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The transmission dynamics of groups A and B human respiratory syncytial virus (hRSV) in England & Wales and Finland: seasonality and cross-protection [PDF]

, 2005
Human respiratory syncytial virus (hRSV) transmission dynamics are inherently cyclical, and the observed genetic diversity (between groups A and B) also appears to have a repeating pattern.
Waris, M, White, Lisa, Medley, GF, White, L. J., Medley, Graham, Waris, M., Cane, Patricia, Nokes, D. James, Nokes, DJ, White, LJ, Cane, PA   +10 more
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Parental and household smoking and the increased risk of bronchitis, bronchiolitis and other lower respiratory infections in infancy: systematic review and meta-analysis [PDF]

, 2011
Background: Passive smoke exposure increases the risk of lower respiratory infection (LRI) in infants, but the extensive literature on this association has not been systematically reviewed for nearly ten years.
Hashim, Ahmed, Jones, Laura L; id_orcid, Leonardi-Bee, J, Ahmed Hashim, Derek G Cook, Britton, J, John Britton, Laura L Jones, Britton John, McKeever Tricia, Cook, Derek G, Leonardi-Bee, Jo, Jones, LL, Cook Derek G, McKeever, Tricia, Britton, John, Leonardi-Bee Jo, Hashim, A, Jo Leonardi-Bee, McKeever, T, Cook, DG, Hashim Ahmed, Jones Laura L, Tricia McKeever   +23 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Evidence of virus interference? Increased risk of non-influenza respiratory virus infections associated with receipt of inactivated influenza vaccine [PDF]

, 2012
BACKGROUND: Seasonal influenza vaccination is effective in preventing influenza infection and disease in healthy school-age children, while influenza vaccination is not generally thought to affect the risk of non-influenza respiratory virus infections (e.
Nishiura, H, Peiris, JSM, Cowling, BJ, Ip, DKM, Leung, GM, Chan, KH, Ng, S, Chiu, SS, Fang, VJ   +8 more
core  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source