Results 71 to 80 of about 112,452 (299)

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Respiratory mechanics in infants with severe bronchiolitis on controlled mechanical ventilation

BMC Pulmonary Medicine, 2017
Background Analysis of respiratory mechanics during mechanical ventilation (MV) is able to estimate resistive, elastic and inertial components of the working pressure of the respiratory system.
Pablo Cruces, Sebastián González-Dambrauskas, Julio Quilodrán, Jorge Valenzuela, Javier Martínez, Natalia Rivero, Pablo Arias, Franco Díaz   +7 more
doaj   +1 more source

Propulsion in a viscoelastic fluid

, 2007
Flagella beating in complex fluids are significantly influenced by viscoelastic stresses. Relevant examples include the ciliary transport of respiratory airway mucus and the motion of spermatozoa in the mucus-filled female reproductive tract. We consider
Bird R. B., Bird R. B., Blake J. R., Blake J. R., Bray D., Denton R., Doi M., Dunn P. F., Eliezer N., Eric Lauga, Gelman R. A., Gilboa A., Giordano A. M., Gray J., Gueron S., Gueron S., Hayat T., Ho H. C., James S. L., Katz D. F., Katz D. F., King M., Larson R. G., Larson R. G., Lillehoj E. P., Liron N., Litt M., Litt M., Meyer F. A., Meyer F. A., Ross S. M., Shake M. P., Suarez S. S., Suarez S. S., Suarez S. S., Suarez S. S., Tam P. Y., Tanner R. I., Wolf D. P., Wolf D. P., Wolf D. P., Wolf D. P., Wolf D. P., Yates G. T.   +43 more
core   +1 more source

Longitudinal Changes in Response to a Cycle-Run Field Test of Young Male National "Talent identification" and Senior Elite Triathlon Squads. [PDF]

, 2012
This study investigated the changes in cardiorespiratory response and running performance of 9 male ?Talent Identification? (TID) and 6 male Senior Elite (SE) Spanish National Squad triathletes during a specific cycle-run test.
Alves, Francisco B., Benito Peinado, Pedro José, Calderón Montero, Francisco Javier, Díaz Molina, Víctor, García Zapico, Augusto, Peinado Lozano, Ana Belen, Vleck, Veronica E., Álvarez Sánchez, María   +7 more
core   +2 more sources

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

The physiology and biomechanics of avian flight at high altitude [PDF]

, 2006
Many birds fly at high altitude, either during long-distance flights or by virtue of residence in high-elevation habitats. Among the many environmental features that vary systematically with altitude, five have significant consequences for avian flight ...
Altshuler, Douglas L., Dudley, Robert
core  

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Can you calculate the total respiratory, lung, and chest wall respiratory mechanics?

Journal of Mechanical Ventilation, 2020
Figure: Waveforms for a patient undergoing mechanical ventilation with volume-controlled mode. Tidal Volume of 500 ml, PEEP 15, Constant inspiratory flow of 45 l/min A: Airway pressure in cmH2O, B: Esophageal pressure in cmH2O, C: Trans-pulmonary ...
Mia Shokry, Kimiyo Yamasaki, Ehab G. Daoud   +2 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Alterations in Respiratory Mechanics and Neural Respiratory Drive After Restoration of Spontaneous Circulation in a Porcine Model Subjected to Different Downtimes of Cardiac Arrest

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background The potential alterations of respiratory pathophysiology after cardiopulmonary resuscitation (CPR) are relatively undefined. While untreated arrest is known to affect post–cardiopulmonary resuscitation circulation, whether it affects ...
Zhengfei Yang, Houzhen Zheng, Lin Lin, Jingying Hou, Cai Wen, Yue Wang, Qin Ling, Longyuan Jiang, Wanchun Tang, Rui Chen   +9 more
doaj   +1 more source